Protein Alignment eIF2Bbeta and eif2b4

DIOPT Version :9

• Sequence 1: NP_570020.1
• Gene: eIF2Bbeta / 31256
• FlyBaseID: FBgn0024996
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: XP_005160517.1
• Gene: eif2b4 / 541548
• ZFINID: ZDB-GENE-030131-955
• Length: 555
• Species: Danio rerio
• Alignment Length: 366
• Identity: 87/366 - (23%)
• Similarity: 145/366 - (39%)
• Gaps: 86/366 - (23%)

  Fly     2 KEQPLKEIT---QLIHAIKV--------GLVEGSYNITNKTLDIFKYIIMSKSW-QNADALMQIV 54
            |..|.::|:   .:||...|        |::.||...:...|..||.:|...|. .|.:....:|
Zfish   221 KNPPTQQISIPATVIHPSIVRLGLQYSQGIIAGSNARSVALLHAFKQVIQDYSTPPNEELSRDLV 285

  Fly    55 R---------DQCKILQAALPQETVTSNIARRILKLTREEFDLLHAKVQHFADDSQASLSLHKLV 110
            .         .||:.|.|::      .|..:.|.|                        .:..:.
Zfish   286 NKLSPYISFLSQCRPLSASM------GNAIKYIKK------------------------EISNIP 320

  Fly   111 TQTSESNVSVDYSVPQHGLREALLDHLQEVETELETSSENICVQAEEHIHSSEIILTLGHSRSVE 175
            .|..|....        |..:|.:|  ..:..::..:||.|...|.|.|.:.::||..|.|..|.
Zfish   321 NQCKEEEAK--------GKLQACID--SYINEKIILASEAISKYAIEKISNGDVILVYGCSSLVN 375

  Fly   176 NFLKRAIKKRQFLTIIVAECAPACRGHNLAASLANEKNVEIVVIPDAAIFAMMSRVNKVIIGTHS 240
            :.|..|.:|::...:||.:..|...|......|. :|.:....:..:|:..::..|:||.:|.|:
Zfish   376 HILCEAFEKQRQFRVIVVDSRPRLEGREALRRLV-KKGIRCTYVLISALSYILPEVSKVFLGAHA 439

  Fly   241 VLANGGLRAACGAYTVALAAKHYSVPVIVLAPMYKLSPLHLCEQ---DAFNMVGCAEDVIPYDSI 302
            :||||.:.:..|...:||.||.|:|||:|....||     .||:   |:| :....:|  |.|.|
Zfish   440 LLANGYVMSRVGTSQIALVAKAYNVPVLVCCETYK-----FCERVQTDSF-VSNELDD--PDDLI 496

  Fly   303 PAREAKVY-------------SPMFDYVPPELVTLFISNTG 330
            ..|..|.:             :.::|..||:.|.|.|::.|
Zfish   497 VTRNGKTHLENWQTVKSLGLLNLVYDVTPPDFVDLVITDLG 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Bbeta	NP_570020.1	GCD2	8..345	CDD:275543	85/360 (24%)
		IF-2B	21..334	CDD:279362	80/336 (24%)
eif2b4	XP_005160517.1	GCD2	235..549	CDD:224105	84/352 (24%)
		IF-2B	251..541	CDD:279362	80/336 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910