Protein Alignment eIF2Bbeta and eif2b2

DIOPT Version :9

• Sequence 1: NP_570020.1
• Gene: eIF2Bbeta / 31256
• FlyBaseID: FBgn0024996
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_001164986.1
• Gene: eif2b2 / 496931
• XenbaseID: XB-GENE-974089
• Length: 351
• Species: Xenopus tropicalis
• Alignment Length: 351
• Identity: 160/351 - (45%)
• Similarity: 238/351 - (67%)
• Gaps: 15/351 - (4%)

  Fly     8 EITQLIHAIKVGLVEG-----SYNITNKTLDIFKYIIMSKSWQNADALMQIVRDQCKILQAALPQ 67
            |:::.|.|....|..|     |.......:.:.:.||....|.||..||:|:|.:.:.:.||.|.
 Frog    10 ELSERIEAFVAQLKRGGGRPNSEETARDPVGLLRRIIAQARWGNAGELMEIIRREGRRMTAAQPS 74

  Fly    68 ETVTSNIARRILKLTREEFDLLHAKVQHFADDSQASLSLHKLVTQTSESNVSVDYSVPQHGLREA 132
            ||...|:.||:|||.|||:    .:::..::::....|||:|:|   ...:|.|::.|...|:..
 Frog    75 ETTVGNMVRRVLKLIREEY----GRLRGCSEENDQQESLHRLIT---AERLSDDFNTPLPLLKAN 132

  Fly   133 LLDHLQEVETELETSSENICVQAEEHIHSSEIILTLGHSRSVENFLKRAIKKRQFLTIIVAECAP 197
            :::.:.|:..|||.:::||.:||:|||||:|:|:|:|.||:|:.||:.|.:||.| .:|||||||
 Frog   133 VIEAVNELLIELEGTTDNIAIQAKEHIHSNEVIMTIGRSRTVQLFLEEAARKRTF-HVIVAECAP 196

  Fly   198 ACRGHNLAASLANEKNVEIVVIPDAAIFAMMSRVNKVIIGTHSVLANGGLRAACGAYTVALAAKH 262
            .|:||::|||| ::..:|..|||||||||:|||||||||||.::||||.|||..|.:|:||||:|
 Frog   197 FCQGHDMAASL-SKAGIETTVIPDAAIFAVMSRVNKVIIGTKTILANGSLRAVSGTHTLALAARH 260

  Fly   263 YSVPVIVLAPMYKLSPLHLCEQDAFNMVGCAEDVIPY-DSIPAREAKVYSPMFDYVPPELVTLFI 326
            :|.|:||.|||:||||....|:|:|:.....::|:|: :.....:...|.|:||:|||||:||||
 Frog   261 HSTPLIVCAPMFKLSPQFPNEEDSFHKFVSPQEVLPFSEGEILSQVSAYCPIFDHVPPELITLFI 325

  Fly   327 SNTGGHAPSYVYRLLTELYHPEDLEI 352
            ||.||:||||:|||::|||||.|.|:
 Frog   326 SNIGGNAPSYIYRLMSELYHPSDHEL 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Bbeta	NP_570020.1	GCD2	8..345	CDD:275543	154/342 (45%)
		IF-2B	21..334	CDD:279362	142/318 (45%)
eif2b2	NP_001164986.1	GCD2	13..344	CDD:224105	153/339 (45%)
		IF-2B	31..333	CDD:279362	141/310 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	270	1.000	Domainoid score	I1807
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6507
Inparanoid	1	1.050	300	1.000	Inparanoid score	I2654
OMA	1	1.010	-	-		QHG54382
OrthoDB	1	1.010	-	-		D396237at33208
OrthoFinder	1	1.000	-	-		FOG0005038
OrthoInspector	1	1.000	-	-		oto102451
Panther	1	1.100	-	-	LDO	PTHR45859
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R372
SonicParanoid	1	1.000	-	-		X4090
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110