Protein Alignment eIF2Bbeta and eif-2Bbeta

DIOPT Version :9

• Sequence 1: NP_570020.1
• Gene: eIF2Bbeta / 31256
• FlyBaseID: FBgn0024996
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_493014.1
• Gene: eif-2Bbeta / 173067
• WormBaseID: WBGene00012950
• Length: 340
• Species: Caenorhabditis elegans
• Alignment Length: 349
• Identity: 94/349 - (26%)
• Similarity: 166/349 - (47%)
• Gaps: 56/349 - (16%)

  Fly    22 EGSYNITNKTLDIFKYIIMSKSWQNADALMQIVRDQCKILQAALPQETVTSNIARRILKLTREEF 86
            :.|.:|...|:::.:.||..::.:..:.|...:.:.||.|..|...|.:..||...|.||.|:|
 Worm    25 DSSSSIAIATVNLIRKIIFRENPKTMNDLQVSLANHCKKLHGAERSELIIINIGLMITKLARDE- 88

  Fly    87 DLLHAK--------VQHFADDSQASLSLHKLVTQTSESNVSVDYSVPQHGLREALLDHLQEVETE 143
             :|..|        ...:.||.:   ::.||.|...:.            :::.|...::|:.||
 Worm    89 -VLQKKGGGEPEPLYTLWRDDDE---TIKKLKTADMKK------------IKKDLQASIKELVTE 137

  Fly   144 LETSSENICVQAEEHIHSSEIIL--TLGHSRSVENFLKRAIKKRQFLTIIVAECAPACRGHNLAA 206
            :|:|.|.|..|:.|.:.:::::|  :|..|:::.|||..|:|              :.|.|.:..
 Worm   138 IESSRECIASQSTELLFNNDVVLVHSLRSSQTMHNFLSHAVK--------------SGRKHRVID 188

  Fly   207 SLANEKNVEIVVIPDAA-------IFAMMSRVNKVIIGTHSVLANGGLRAACGAYTVALAAKHYS 264
            .:..|:::|..  ||.|       :.:.|...:||::...:...:|......|.:.:||.||.:.
 Worm   189 VVDEEEHIEST--PDFATAIELYEVASKMPEASKVVLVAAAYFPDGSCLVPAGGHQIALLAKRHC 251

  Fly   265 VPVIVLAPMYKLSPLHLCEQDAFNMVGCAEDVIPYDSIPAREAKVYS---PMFDYVPPELVTLFI 326
            |||.||||.|||.|..:...|:.:..  ..:.:|:| :.|:.|.:..   |.||.:..:|||||:
 Worm   252 VPVYVLAPFYKLCPFFMTNPDSLHTF--RSNSLPFD-LSAKSAGLVDCLHPAFDCLQSDLVTLFV 313

  Fly   327 SNTGGHAPSYVYRLLTELYHPEDL 350
            |||....||:|.||..:.||.:|:
 Worm   314 SNTSCVIPSHVNRLKEDYYHSQDI 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Bbeta	NP_570020.1	GCD2	8..345	CDD:275543	91/342 (27%)
		IF-2B	21..334	CDD:279362	86/331 (26%)
eif-2Bbeta	NP_493014.1	GCD2	<124..332	CDD:275543	66/226 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159816
Domainoid	1	1.000	95	1.000	Domainoid score	I4672
eggNOG	1	0.900	-	-		E1_COG1184
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	111	1.000	Inparanoid score	I3446
Isobase	1	0.950	-	0	Normalized mean entropy	S1701
OMA	1	1.010	-	-		QHG54382
OrthoDB	1	1.010	-	-		D396237at33208
OrthoFinder	1	1.000	-	-		FOG0005038
OrthoInspector	1	1.000	-	-		oto18900
orthoMCL	1	0.900	-	-		OOG6_102470
Panther	1	1.100	-	-	LDO	PTHR45859
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R372
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.790