Protein Alignment eIF2Bbeta and Eif2b4

DIOPT Version :9

• Sequence 1: NP_570020.1
• Gene: eIF2Bbeta / 31256
• FlyBaseID: FBgn0024996
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_001120827.1
• Gene: Eif2b4 / 13667
• MGIID: 95300
• Length: 544
• Species: Mus musculus
• Alignment Length: 359
• Identity: 90/359 - (25%)
• Similarity: 150/359 - (41%)
• Gaps: 91/359 - (25%)

  Fly    10 TQLIHAIKV--------GLVEGSYNITNKTLDIFKYIIMSKSWQNA------DALMQIVRDQCKI 60
            :.:||...|        ||:.||                     ||      .||.|:::|
Mouse   221 SSVIHPAMVRLGLQYSQGLISGS---------------------NARCIALLHALQQVIQD---- 260

  Fly    61 LQAALPQETVTSNIARRILKLTREEFDLLHAKVQHFADDSQASLS-------LHKLVTQTSESNV 118
             ....|.|           :|:|:..:.|...:.........|.|       |.|.||..|.|..
Mouse   261 -YTTPPSE-----------ELSRDLVNKLKPYISFLTQCRPMSASMCNAIKFLTKEVTGMSSSKR 313

  Fly   119 SVDYSVPQHGLREALLDHLQEVETELETSSENICVQAEEHIHSSEIILTLGHSRSVENFLKRA-I 182
            ..:   .:..|||||..::||   ::..:::.|...|...|...::||..|.|..|...|:.| :
Mouse   314 EEE---AKSELREALDRYVQE---KIVLAAQAISRFASTKISDGDVILVYGCSSLVSRILQEARV 372

  Fly   183 KKRQFLTIIVAECAPACRGHNLAASLANE-KNVEIVVIPDAAIFAMMSRVNKVIIGTHSVLANGG 246
            :.|:| .::|.:..|...|.::..||... .....::||.|:.  ::..|:||::|.|::||||.
Mouse   373 EGRRF-RVVVVDSRPRLEGRHMLHSLVRAGVPTSYLLIPAASY--VLPEVSKVLLGAHALLANGS 434

  Fly   247 LRAACGAYTVALAAKHYSVPVIVLAPMYKLSPLHLCEQ---DAF--NMVGCAED----------V 296
            :.:..|...:||.|:.::|||:|....||     .||:   |||  |.:...:|          :
Mouse   435 VMSRVGTAQLALVARAHNVPVLVCCETYK-----FCERVQTDAFVSNELDDPDDLQCKRGDQVAL 494

  Fly   297 IPYDSIPAREAKVYSPMFDYVPPELVTLFISNTG 330
            ..:.|.|:  .::.:.::|..|||||.|.|:..|
Mouse   495 ANWQSHPS--LRLLNLVYDVTPPELVDLVITELG 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF2Bbeta	NP_570020.1	GCD2	8..345	CDD:275543	90/359 (25%)
		IF-2B	21..334	CDD:279362	85/340 (25%)
Eif2b4	NP_001120827.1	GCD2	240..538	CDD:224105	85/340 (25%)
		IF-2B	240..530	CDD:279362	85/340 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810