DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugalt and MFSD14A

DIOPT Version :9

Sequence 1:	NP_001138149.1	Gene:	Ugalt / 31255	FlyBaseID:	FBgn0024994	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	NP_149044.2	Gene:	MFSD14A / 64645	HGNCID:	23363	Length:	490	Species:	Homo sapiens

Alignment Length:	321	Identity:	67/321 - (20%)
Similarity:	108/321 - (33%)	Gaps:	75/321 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 ITCLFLVFNEEGKDAQKFVRSLHKTIIANPMDTLKVCVPSLVYIVQNNLLYVSASHLDAATYQVT 131
            :..:||.|...|......:..||:|.   |..|.  .:..|:..|:..|.::||..:.|.:....
Human    41 VIVIFLEFFAWGLLTAPTLVVLHETF---PKHTF--LMNGLIQGVKGLLSFLSAPLIGALSDVWG 100

  Fly   132 YQLKILTTAMFAVVILRRKLLNTQWGALLLLVMGIVLVQLAQ--------TEGPTSGSAGGAAAA 188
            .:..:|.|..|....:....::..|...::.|.|:..|..:.        |:......|.|..:|
Human   101 RKSFLLLTVFFTCAPIPLMKISPWWYFAVISVSGVFAVTFSVVFAYVADITQEHERSMAYGLVSA 165

  Fly   189 ATAASSGGAPEQNRMLG-------------LWAALGACF-LSGFAGIYFEKILK---GAEISVWM 236
            ..|||...:|.....||             ..|.|..|| |........||:..   ||.|| |.
Human   166 TFAASLVTSPAIGAYLGRVYGDSLVVVLATAIALLDICFILVAVPESLPEKMRPASWGAPIS-WE 229

  Fly   237 RNVQLSLLSIPFG-----------LLTCFVNDGSRIFDQGFFKGYDLFVWYLVLLQAGGGLIVAV 290
            :       :.||.           ||.|.....|.:.:.|.:..:     :|.|.|
Human   230 Q-------ADPFASLKKVGQDSIVLLICITVFLSYLPEAGQYSSF-----FLYLRQ--------- 273

  Fly   291 VVKYADNILKGFATSLAIIISCVASIYIFDF--------NLTLQFSFGAGLVIASIFLYGY 343
            ::|::...:..|...|. |:|.:|...:...        |..|   .|.|..|..:..||:
Human   274 IMKFSPESVAAFIAVLG-ILSIIAQTIVLSLLMRSIGNKNTIL---LGLGFQILQLAWYGF 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugalt	NP_001138149.1	Nuc_sug_transp	18..342	CDD:282054	65/318 (20%)
Ugalt	NP_001138149.1	EamA	101..341	CDD:304911	56/283 (20%)
MFSD14A	NP_149044.2	MFS_MFSD14	37..449	CDD:340945	67/321 (21%)
MFSD14A	NP_149044.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	465..490
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910