DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugalt and slc35a2

DIOPT Version :9

Sequence 1:	NP_001138149.1	Gene:	Ugalt / 31255	FlyBaseID:	FBgn0024994	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	XP_005166767.1	Gene:	slc35a2 / 555288	ZFINID:	ZDB-GENE-030616-62	Length:	379	Species:	Danio rerio

Alignment Length:	345	Identity:	170/345 - (49%)
Similarity:	232/345 - (67%)	Gaps:	14/345 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 TYSYSHRTVNANTLKYISLLTLTLQNAILGLSMRYARTRPGDIFLSSTAVLMAEFAKLITCLFLV 73
            |.|.....|| ..|||.||..|.:|||.|.||:||.||.|||.|.:::||:|||..|:|||||::
Zfish    20 TSSRRQNEVN-KKLKYTSLAILVIQNASLILSIRYVRTLPGDHFYTTSAVVMAEVLKVITCLFII 83

  Fly    74 FNEEGKDAQKFVRSLHKTIIANPMDTLKVCVPSLVYIVQNNLLYVSASHLDAATYQVTYQLKILT 138
            ..::..:.:.||..|:.:|:....||||:.||||:|.:||||.||:.|:|.|||:||||||||||
Zfish    84 LIQKRGNVKSFVSLLYDSIVIQYWDTLKLAVPSLIYTLQNNLQYVAISNLPAATFQVTYQLKILT 148

  Fly   139 TAMFAVVILRRKLLNTQWGALLLLVMGIVLVQLAQTEGPTSGSAGGAAAAATAASSGGAPEQNRM 203
            ||:|:|::||:.|...||.:|:||..|:.:||:.|       .:|....|.|||:      ||..
Zfish   149 TALFSVLMLRKSLSRIQWISLVLLFAGVAIVQVEQ-------ESGKQKEAVTAAN------QNYF 200

  Fly   204 LGLWAALGACFLSGFAGIYFEKILKGAEISVWMRNVQLSLLSIPFGLLTCFVNDGSRIFDQGFFK 268
            .||.:.:.:|..|||||:||||||||:..||||||:||.:.....|||..:.|||:.|.::||..
Zfish   201 KGLLSVIISCLSSGFAGVYFEKILKGSSASVWMRNIQLGIFGTVLGLLGMWWNDGAAIAEKGFLF 265

  Fly   269 GYDLFVWYLVLLQAGGGLIVAVVVKYADNILKGFATSLAIIISCVASIYIFDFNLTLQFSFGAGL 333
            ||...||.::..||.|||:||||||||||||||||||.:||:|.:.|:|:|.|::.|.|:.||||
Zfish   266 GYTPMVWGVIFNQAFGGLLVAVVVKYADNILKGFATSFSIIVSTITSVYLFGFHVDLVFTLGAGL 330

  Fly   334 VIASIFLYGYDPARSAPKPT 353
            ||.::::|....|.::...|
Zfish   331 VIGAVYMYSLPKANTSTSST 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugalt	NP_001138149.1	Nuc_sug_transp	18..342	CDD:282054	164/323 (51%)
Ugalt	NP_001138149.1	EamA	101..341	CDD:304911	125/239 (52%)
slc35a2	XP_005166767.1	Nuc_sug_transp	31..339	CDD:282054	163/320 (51%)
slc35a2	XP_005166767.1	nst	111..338	CDD:129885	125/239 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593079
Domainoid	1	1.000	312	1.000	Domainoid score	I1283
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38085
Inparanoid	1	1.050	315	1.000	Inparanoid score	I2543
OMA	1	1.010	-	-		QHG57961
OrthoDB	1	1.010	-	-		D540031at33208
OrthoFinder	1	1.000	-	-		FOG0000573
OrthoInspector	1	1.000	-	-		otm26118
orthoMCL	1	0.900	-	-		OOG6_100998
Panther	1	1.100	-	-	LDO	PTHR10231
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R502
SonicParanoid	1	1.000	-	-		X1127
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	15	14.940