DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugalt and Slc35a2

DIOPT Version :9

Sequence 1:	NP_001138149.1	Gene:	Ugalt / 31255	FlyBaseID:	FBgn0024994	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	NP_511039.2	Gene:	Slc35a2 / 22232	MGIID:	1345297	Length:	393	Species:	Mus musculus

Alignment Length:	389	Identity:	189/389 - (48%)
Similarity:	245/389 - (62%)	Gaps:	46/389 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ALLPAPVTYSYSHRTVNANTLKYISLLTLTLQNAILGLSMRYARTRPGDIFLSSTAVLMAEFAKL 66
            ||.|...|  .:||     .||||||..|.:|||.|.||:|||||.|||.|.::|||:|||..|.
Mouse    22 ALEPGSTT--AAHR-----RLKYISLAVLVVQNASLILSIRYARTLPGDRFFATTAVVMAEVLKG 79

  Fly    67 ITCLFLVFNEEGKDAQKFVRSLHKTIIANPMDTLKVCVPSLVYIVQNNLLYVSASHLDAATYQVT 131
            :|||.|:|.::..:.:..|..||:.::...:||||:.||||:|.:||||.||:.|:|.|||:|||
Mouse    80 LTCLLLLFAQKRGNVKHLVLFLHEAVLVQYVDTLKLAVPSLIYTLQNNLQYVAISNLPAATFQVT 144

  Fly   132 YQLKILTTAMFAVVILRRKLLNTQWGALLLLVMGIVLVQLAQTEGPTSGSAGGAAAAATAASSGG 196
            |||||||||:|:|::|.|.|...||.:||||..|:.:||..|        |||         ||.
Mouse   145 YQLKILTTALFSVLMLNRSLSRLQWASLLLLFTGVAIVQAQQ--------AGG---------SGP 192

  Fly   197 AP-EQNRMLGLWAALGACFLSGFAGIYFEKILKGAEISVWMRNVQLSLLSIPFGLLTCFVNDGSR 260
            .| :||...||.|.:.:|..|||||:||||||||:..|||:||:||.|.....||:..:..:|:.
Mouse   193 RPLDQNPGAGLAAVVASCLSSGFAGVYFEKILKGSSGSVWLRNLQLGLFGTALGLVGLWWAEGTA 257

  Fly   261 IFDQGFFKGYDLFVWYLVLLQAGGGLIVAVVVKYADNILKGFATSLAIIISCVASIYIFDFNLTL 325
            :..||||.||...||.:||.||.|||:|||||||||||||||||||:|::|.||||.:|.|:|..
Mouse   258 VASQGFFFGYTPAVWGVVLNQAFGGLLVAVVVKYADNILKGFATSLSIVLSTVASIRLFGFHLDP 322

  Fly   326 QFSFGAGLVIASIFLYGYD-------PARSAPKPTMH--GPG----------GD--EEKLLPRV 368
            .|:.||||||.:::||...       .:.||..|.:|  .||          ||  .|..||::
Mouse   323 LFALGAGLVIGAVYLYSLPRGAVKAIASASASGPCIHQQPPGQPPPPQLSSRGDLTTEPFLPKL 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugalt	NP_001138149.1	Nuc_sug_transp	18..342	CDD:282054	171/324 (53%)
Ugalt	NP_001138149.1	EamA	101..341	CDD:304911	130/240 (54%)
Slc35a2	NP_511039.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24		1/1 (100%)
		Nuc_sug_transp	31..339	CDD:282054	173/329 (53%)
		nst	114..338	CDD:129885	130/240 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847705
Domainoid	1	1.000	310	1.000	Domainoid score	I1321
eggNOG	1	0.900	-	-		E1_COG0697
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38085
Inparanoid	1	1.050	310	1.000	Inparanoid score	I2575
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57961
OrthoDB	1	1.010	-	-		D540031at33208
OrthoFinder	1	1.000	-	-		FOG0000573
OrthoInspector	1	1.000	-	-		oto93427
orthoMCL	1	0.900	-	-		OOG6_100998
Panther	1	1.100	-	-	LDO	PTHR10231
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R502
SonicParanoid	1	1.000	-	-		X1127
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.800