DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugalt and SLC35G1

DIOPT Version :9

Sequence 1:	NP_001138149.1	Gene:	Ugalt / 31255	FlyBaseID:	FBgn0024994	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	NP_001128130.1	Gene:	SLC35G1 / 159371	HGNCID:	26607	Length:	365	Species:	Homo sapiens

Alignment Length:	329	Identity:	63/329 - (19%)
Similarity:	126/329 - (38%)	Gaps:	103/329 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 LMAEFAKLITCLFLVFNEEGKDAQKFVRSLHKTIIA--NPMDTLKVCVPSLVY------------ 109
            |::.|...:..||:          |.|:.:|...|:  ..:..:.|.:|.|:|
Human    76 LLSAFLFSVGSLFV----------KKVQDVHAVEISAFRCVFQMLVVIPCLIYRKTGFIGPKGQR 130

  Fly   110 --IVQNNLLYVSASHLDAATYQ---------VTYQLKILTTAMFAVVILRRKLLNTQWGAL--LL 161
              ::...:|..:|..|....||         :|:...:. |::||.:.|:.|.  :.|.||  :.
Human   131 IFLILRGVLGSTAMMLIYYAYQTMSLADATVITFSSPVF-TSIFAWICLKEKY--SPWDALFTVF 192

  Fly   162 LVMGIVLVQL------AQTEGPTSGSAGGAAAAATAASSGGAPEQNRMLGLWAALGACFLSGFAG 220
            .:.|::|:..      :.|.|.....:|                  .:.|.:||:|:...:....
Human   193 TITGVILIVRPPFLFGSDTSGMEESYSG------------------HLKGTFAAIGSAVFAASTL 239

  Fly   221 IYFEKILKGAE--ISVWMRNVQ--------LSLL---SIPFGLLTCFVNDGSRIFDQGFFKGYD- 271
            :...|:.|..:  :|:|...|.        ||:|   |:|:    |               |.|
Human   240 VILRKMGKSVDYFLSIWYYVVLGLVESVIILSVLGEWSLPY----C---------------GLDR 285

  Fly   272 LFVWYLVLLQAGGGLIV--AVVVKYADNILKGFATSLAIIISCVASIYIFDFNLTLQFSFGAGL- 333
            ||:.::.|...||.:.:  |:.::.|..:  ....::.::.:.:..|..|: |:...::.|..|
Human   286 LFLIFIGLFGLGGQIFITKALQIEKAGPV--AIMKTMDVVFAFIFQIIFFN-NVPTWWTVGGALC 347

  Fly   334 VIAS 337
            |:||
Human   348 VVAS 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugalt	NP_001138149.1	Nuc_sug_transp	18..342	CDD:282054	63/329 (19%)
Ugalt	NP_001138149.1	EamA	101..341	CDD:304911	55/285 (19%)
SLC35G1	NP_001128130.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..33
SLC35G1	NP_001128130.1	RhaT	70..359	CDD:223769	63/329 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0697
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900