DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugalt and Slc35a2

DIOPT Version :9

Sequence 1:	NP_001138149.1	Gene:	Ugalt / 31255	FlyBaseID:	FBgn0024994	Length:	368	Species:	Drosophila melanogaster
Sequence 2:	XP_038955312.1	Gene:	Slc35a2 / 100158233	RGDID:	2293497	Length:	423	Species:	Rattus norvegicus

Alignment Length:	419	Identity:	189/419 - (45%)
Similarity:	246/419 - (58%)	Gaps:	76/419 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ALLPAPVTYSYSHRTVNANTLKYISLLTLTLQNAILGLSMRYARTRPGDIFLSSTAVLMAEFAKL 66
            ||.|...|  .:||     .||||||..|.:|||.|.||:|||||.|||.|.::|||:|||..|.
  Rat    22 ALEPGSAT--AAHR-----RLKYISLAVLVVQNASLILSIRYARTLPGDRFFATTAVVMAEVLKG 79

  Fly    67 ITCLFLVFNEEGKDAQKFVRSLHKTIIANPMDTLKVCVPSLVYIVQNNLLYVSASHLDAATY--- 128
            :|||.|:|.::..:.:..|..||:.::...:||||:.||||:|.:||||.||:.|:|.|||:
  Rat    80 LTCLLLLFAQKRGNVKHLVLFLHEAVLVQYVDTLKLAVPSLIYTLQNNLQYVAISNLPAATFQAH 144

  Fly   129 -------------------------QVTYQLKILTTAMFAVVILRRKLLNTQWGALLLLVMGIVL 168
                                     ||||||||||||:|:|::|.|.|...||.:||||..|:.:
  Rat   145 SGCCPKPLALSGSWDQPSVPSTCNLQVTYQLKILTTALFSVLMLNRSLSRLQWASLLLLFTGVAI 209

  Fly   169 VQLAQTEGPTSGSAGGAAAAATAASSGGAP-EQNRMLGLWAALGACFLSGFAGIYFEKILKGAEI 232
            ||..|        |||         ||..| :||..:||.|.:.:|..|||||:||||||||:..
  Rat   210 VQAQQ--------AGG---------SGPRPLDQNPGVGLAAVVASCLSSGFAGVYFEKILKGSSG 257

  Fly   233 SVWMRNVQLSLLSIPFGLLTCFVNDGSRIFDQGFFKGYDLFVWYLVLLQAGGGLIVAVVVKYADN 297
            |||:||:||.|.....||:..:..:|:.:..||||.||...||.:||.||.|||:||||||||||
  Rat   258 SVWLRNLQLGLFGTALGLVGLWWAEGTAVASQGFFFGYTPAVWGVVLNQAFGGLLVAVVVKYADN 322

  Fly   298 ILKGFATSLAIIISCVASIYIFDFNLTLQFSFGAGLVIASIFLYGY---------DPARSAPKPT 353
            |||||||||:|::|.||||.:|.|:|...|:.||||||.:::||..         ..:.||..|.
  Rat   323 ILKGFATSLSIVLSTVASIRLFGFHLDPLFALGAGLVIGAVYLYSLPRGAVKAIASASASASGPC 387

  Fly   354 MH--GPG----------GD--EEKLLPRV 368
            :|  .||          ||  .|..||::
  Rat   388 IHQQPPGQPPPPQLSSRGDLITEPFLPKL 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugalt	NP_001138149.1	Nuc_sug_transp	18..342	CDD:282054	171/352 (49%)
Ugalt	NP_001138149.1	EamA	101..341	CDD:304911	130/268 (49%)
Slc35a2	XP_038955312.1	Nuc_sug_transp	31..367	CDD:398009	173/357 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351277
Domainoid	1	1.000	311	1.000	Domainoid score	I1272
eggNOG	1	0.900	-	-		E1_COG0697
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38085
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2512
OMA	1	1.010	-	-		QHG57961
OrthoDB	1	1.010	-	-		D540031at33208
OrthoFinder	1	1.000	-	-		FOG0000573
OrthoInspector	1	1.000	-	-		oto96968
orthoMCL	1	0.900	-	-		OOG6_100998
Panther	1	1.100	-	-	LDO	PTHR10231
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1127
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810