Protein Alignment CG2662 and PHC3

DIOPT Version :9

• Sequence 1: NP_001284832.1
• Gene: CG2662 / 31254
• FlyBaseID: FBgn0024993
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: XP_005247846.1
• Gene: PHC3 / 80012
• HGNCID: 15682
• Length: 1011
• Species: Homo sapiens
• Alignment Length: 505
• Identity: 103/505 - (20%)
• Similarity: 166/505 - (32%)
• Gaps: 183/505 - (36%)

  Fly     3 QSKDEDKEESPVQPTTHNSSAGSNGHDAKSPVVTTAPAATC---------------SVSVSDASG 52
            |.:|..:||.|      ..|......|...|..|.:|||..               .|.:...:.
Human   615 QVEDVCEEEMP------EESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVAS 673

  Fly    53 AGASVRTTGRVKKPKQVYDPSDNYV---------SRASSNRNSL-SSVPATSNVQSPP------- 100
            ..|||     :|.|.   |||...|         :...||..|: ||:|:..|  .||
Human   674 VSASV-----IKSPS---DPSHVSVPPPPLLLPAATTRSNSTSMHSSIPSIEN--KPPQAIVKPQ 728

  Fly   101 ----VKEATDSQDSTTS-PVSEQQ---QQQLQQAAQLRNFDTCQKCGKSEPKRGSGHKSN----- 152
                |.|....|:.... |||...   :|.:::...|.|......|.:.|.:..:.|..|
Human   729 ILTHVIEGFVIQEGLEPFPVSRSSLLIEQPVKKRPLLDNQVINSVCVQPELQNNTKHADNSSDTE 793

  Fly   153 ----------------FLTCKGCMQKWHFPCLPITFHNQSTARKKFKCDKCRYCRLCNVRGPGLS 201
                            .|.|:.|.:        :.:.|:....|:|
Human   794 MEDMIAEETLEEMDSELLKCEFCGK--------MGYANEFLRSKRF------------------- 831

  Fly   202 ICSL-CVDAYHPDCNDPTLKQSKAVEANPNWRCFRCEACNIGGSTSASSEEQTGARKSTASREDQ 265
             |:: |...|:..|                                        ::|...||.::
Human   832 -CTMSCAKRYNVSC----------------------------------------SKKFALSRWNR 855

  Fly   266 AQPVVPRKSNAGRKKRVQSEPTGQEKAAKIEKLAKRRQPLK-TEKKKEYKKEEDEEPAQIKVKVE 329
            .    |...:.|.:.|   .|:|.:.||:...|  |:.|:. ...:::....||..|:.:..::.
Human   856 K----PDNQSLGHRGR---RPSGPDGAAREHIL--RQLPITYPSAEEDLASHEDSVPSAMTTRLR 911

  Fly   330 KVEPVDMETE--------QIENNDLPGPEQESLSLRLTPITAVERRSHPVSTWSVEQVVQFVAKR 386
            :....:.|.|        ..||:|            |.|:...|     .|.|:|:.|..|:...
Human   912 RQSERERERELRDVRIRKMPENSD------------LLPVAQTE-----PSIWTVDDVWAFIHSL 959

  Fly   387 YPKE--ANVFRYQDIDGASLLLLNRHDVMNGFGLKLGPALRVFELVMSLQ 434
            ...:  |:.||.|:|||.:||||....:|:...:||||||::...:.||:
Human   960 PGCQDIADEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKICARINSLK 1009

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2662	NP_001284832.1	PHD	134..187	CDD:214584	10/73 (14%)
		PHD	189..236	CDD:214584	4/47 (9%)
		SAM_Atherin-like	371..438	CDD:188982	25/66 (38%)
		SAM	371..436	CDD:197735	25/66 (38%)
PHC3	XP_005247846.1	SAM_Ph1,2,3	942..1010	CDD:188976	26/73 (36%)
		SAM	944..1011	CDD:197735	25/66 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910