DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2662 and DPF2

DIOPT Version :9

Sequence 1:	NP_001284832.1	Gene:	CG2662 / 31254	FlyBaseID:	FBgn0024993	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	XP_024304405.1	Gene:	DPF2 / 5977	HGNCID:	9964	Length:	575	Species:	Homo sapiens

Alignment Length:	210	Identity:	54/210 - (25%)
Similarity:	83/210 - (39%)	Gaps:	23/210 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 PAATCSV-SVSDASGAGASVRTTGRVKKPKQVYDPSDNYVSRASSNRNSLSSVPATSNVQSPPVK 102
            |||...| |||..|....|...:...|: |...........:...||..||...|.|::.....:
Human   360 PAAAAPVSSVSRPSSHDFSFCLSDSFKQ-KHTSKAPQRVCGKRYKNRPGLSYHYAHSHLAEEEGE 423

  Fly   103 EATDSQDSTTSPVSEQQQQQLQQ-----AAQLRNFDTCQKC-GKSEPKRGSGHKSNFLTCKGCMQ 161
            :..|||..|  |||::.::|..:     .|...|:  |..| |.|:..:.:|.....::|..|.:
Human   424 DKEDSQPPT--PVSQRSEEQKSKKGPDGLALPNNY--CDFCLGDSKINKKTGQPEELVSCSDCGR 484

  Fly   162 KWHFPCL---PITFHNQSTARKKFKCDKCRYCRLCNV--RGPGLSICSLCVDAYHPDCNDPTLKQ 221
            ..|..||   |:......|.|  ::|.:|:.|.:|..  ....|..|..|...||..|..|::.:
Human   485 SGHPSCLQFTPVMMAAVKTYR--WQCIECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSE 547

  Fly   222 SKAVEANPNWRCFRC 236
                ....:|.|..|
Human   548 ----PPEGSWSCHLC 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2662	NP_001284832.1	PHD	134..187	CDD:214584	14/56 (25%)
		PHD	189..236	CDD:214584	11/48 (23%)
		SAM_Atherin-like	371..438	CDD:188982
		SAM	371..436	CDD:197735
DPF2	XP_024304405.1	Requiem_N	13..79	CDD:316564
		SFP1	<397..417	CDD:227516	6/19 (32%)
		PHD1_DPF2_like	456..511	CDD:277161	14/58 (24%)
		PHD2_d4	513..558	CDD:277005	11/48 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3744
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.860