DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2662 and Scmh1

DIOPT Version :9

Sequence 1:	NP_001284832.1	Gene:	CG2662 / 31254	FlyBaseID:	FBgn0024993	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	XP_038966228.1	Gene:	Scmh1 / 362581	RGDID:	1305788	Length:	718	Species:	Rattus norvegicus

Alignment Length:	376	Identity:	80/376 - (21%)
Similarity:	129/376 - (34%)	Gaps:	75/376 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 RNSLSSVPATSNVQSPPVKEATDSQDSTTSPVSEQQQQQLQQAAQLRNFDTC---QKCGKSEP-- 143
            |..||..|.:....:|....:|..||:.|.|.|..|...:           |   .|.|.:.|
  Rat   373 RTLLSPPPTSPTTSTPEPDTSTVPQDAATIPSSAMQAPTV-----------CIYLNKSGSTGPHL 426

  Fly   144 --KRGSGHKSNFLTCKG--CMQKWHFPCLPITFHNQSTARKKFKCDKCRYCRLCNVRGPGLSICS 204
              |:......:|...:.  .:|:....|:...:| |.|.....|            :|.|..:.|
  Rat   427 DKKKIQQLPDHFGPARASVVLQQAVQACIDCAYH-QKTVFSFLK------------QGHGGEVIS 478

  Fly   205 LCVDAYHPDCNDPTLKQSKAVEANPNWRCFRCEACNIGGSTSASSEEQTGARKSTASREDQAQPV 269
            ...|......|.|.:.....|.......|....:.|:.|:...:....:......:...|:..|.
  Rat   479 AVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHVSLTATEYSHGHDRYLPG 543

  Fly   270 VPRKSNAGRKKRVQSEPTGQEKAAKIEKLAKRRQPLKTEKKKEYKKEEDEEPAQIKVKVEKVEPV 334
            ..........:.:::.....:.|.|...|....|.|:|...:...       ....:.:..|..|
  Rat   544 ETFVLGNSLTRSLETHSDLMDSALKPANLVSTSQTLRTPGYRPLL-------PSCGLPLSTVSAV 601

  Fly   335 -----------DMETEQIEN----NDLPGPEQESLSLRLTPITAVERRSHP------VSTWSVEQ 378
                       ..|...:|:    |..||.::.           :|.|..|      .|:|:||.
  Rat   602 RRLCSRGVLKGTRERRDVESFWKLNHSPGSDRH-----------LESRDPPRLSGRDPSSWTVED 655

  Fly   379 VVQFVAKRYPK---EANVFRYQDIDGASLLLLNRHDVMNGFGLKLGPALRV 426
            |:|||.:..|:   .|::||..:|||.:||||....:|...||||||||::
  Rat   656 VMQFVREADPQLGSHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKL 706

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2662	NP_001284832.1	PHD	134..187	CDD:214584	12/61 (20%)
		PHD	189..236	CDD:214584	8/46 (17%)
		SAM_Atherin-like	371..438	CDD:188982	28/59 (47%)
		SAM	371..436	CDD:197735	28/59 (47%)
Scmh1	XP_038966228.1	MBT	85..180	CDD:214723
		MBT	191..289	CDD:214723
		RBR	324..373	CDD:407329	80/376 (21%)
		SLED	411..519	CDD:403384	22/131 (17%)
		SAM_Scm	645..715	CDD:188977	28/62 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910