Protein Alignment Lint-O and SAMD7

DIOPT Version :10

• Sequence 1: NP_570018.1
• Gene: Lint-O / 31254
• FlyBaseID: FBgn0024993
• Length: 446
• Species: Drosophila melanogaster
• Sequence 2: NP_872416.1
• Gene: SAMD7 / 344658
• HGNCID: 25394
• Length: 446
• Species: Homo sapiens
• Alignment Length: 410
• Identity: 92/410 - (22%)
• Similarity: 142/410 - (34%)
• Gaps: 94/410 - (22%)

  Fly    66 PKQVYDPSD--NYVSRASSNRNSLSS--VPATSNVQSPPVKEATDSQDSTTSPVSEQQQQQLQQA 126
            |:|...||.  :.|...::..|.|||  .|....:....:|......:......:.:.:.::...
Human    41 PRQFCVPSQFGSSVLPNTNMANVLSSRIYPGWGILPPESIKAVARRNEMIQRHHTARTEMEMYAI 105

  Fly   127 AQLRNFDTCQKCGKSEPKRGSGHKSNFLTCKGCMQKWHFPCLPITFHNQSTARKKFKCDKCRYCR 191
            .|.|..:      |..||..:|....||....      .|..|..:|    .|.........:.|
Human   106 YQQRRME------KINPKGLAGLGIPFLYGSS------VPAAPAAYH----GRSMLPAGDLHFHR 154

  Fly   192 --LCNVRGPGLSICSLCVDAYHPDCNDPTLKQSKAVEANPNW--RCFRCEACNIGGSTSASSEEQ 252
              |.|::|                  :|.| .:.|.....:|  ||.|... |.|...:..|:.:
Human   155 STLRNLQG------------------NPML-AATAPHFEESWGQRCRRLRK-NTGNQKALDSDAE 199

  Fly   253 TGARKSTASREDQAQP-VVPRKSNAGRKKRVQSEPTGQEKAAKIEK----LAK--------RRQP 304
            :.  ||.|..:...|. .||.:.:...|......|:.|:.:...||    ||.        .|:|
Human   200 SS--KSQAEEKILGQTHAVPYEEDHYAKDPDIEAPSNQKSSETNEKPTTALANTCGELEPTHRKP 262

  Fly   305 ----LKTEKKKEYKKEEDEEPAQIKVKVEKVEPVDMETEQIENNDLPGPEQ-----ESLSLRLTP 360
                ..|.|.|.:...::|...||....::...|   ...:....|||...     .:|||
Human   263 WGSHTTTLKAKAWDDGKEEASEQIFATCDEKNGV---CPPVPRPSLPGTHALVTIGGNLSL---- 320

  Fly   361 ITAVERRSHPVSTWSVEQVVQFVAKRYP---KEANVFRYQDIDGASLLLLNRHDVMNGFGLKLGP 422
                   ...:..|:|:.|..|: :..|   ..|.||:...|||.:|.||....:....||||||
Human   321 -------DEDIQKWTVDDVHSFI-RSLPGCSDYAQVFKDHAIDGETLPLLTEEHLRGTMGLKLGP 377

  Fly   423 ALRVFELVMSLQTQ-SNDVG 441
            ||::       |:| |..||
Human   378 ALKI-------QSQVSQHVG 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lint-O	NP_570018.1	PHD	134..187	CDD:214584	10/52 (19%)
		PHD	189..236	CDD:214584	10/50 (20%)
		SAM_Atherin-like	371..438	CDD:188982	24/70 (34%)
SAMD7	NP_872416.1	Required for localization to nuclear polycomb bodies. /evidence=ECO:0000250|UniProtKB:Q8C8Y5	94..168		18/108 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	187..207		6/21 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	225..277		12/51 (24%)
		SAM_Samd7,11	324..391	CDD:188978	27/75 (36%)