DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2662 and Dpf2

DIOPT Version :9

Sequence 1:	NP_001284832.1	Gene:	CG2662 / 31254	FlyBaseID:	FBgn0024993	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_001278007.1	Gene:	Dpf2 / 19708	MGIID:	109529	Length:	405	Species:	Mus musculus

Alignment Length:	246	Identity:	61/246 - (24%)
Similarity:	96/246 - (39%)	Gaps:	41/246 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DEDKEESPVQPTTHNSSAGSNGHDAKSPVVTTAPAATCSVSVSDASGAGA---SVRTTGRVKKPK 67
            |||.||.    |......|.    :||..|::|.....:..:.|.....|   |.:.....|.|:
Mouse   169 DEDYEED----TPKRRGKGK----SKSKGVSSARKKLDASILEDRDKPYACDNSFKQKHTSKAPQ 225

  Fly    68 QVYDPSDNYVSRASSNRNSLSSVPATSNVQSPPVKEATDSQDS-TTSPVSEQQQQQLQQ-----A 126
            :|       ..:...||..||...|.|::..   :|..|.:|| ..:|||::.::|..:     .
Mouse   226 RV-------CGKRYKNRPGLSYHYAHSHLAE---EEGEDKEDSRPPTPVSQRSEEQKSKKGPDGL 280

  Fly   127 AQLRNFDTCQKC-GKSEPKRGSGHKSNFLTCKGCMQKWHFPCL---PITFHNQSTARKKFKCDKC 187
            |...|:  |..| |.|:..:.:|.....::|..|.:..|..||   |:......|.|  ::|.:|
Mouse   281 ALPNNY--CDFCLGDSKINKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYR--WQCIEC 341

  Fly   188 RYCRLCNV--RGPGLSICSLCVDAYHPDCNDPTLKQSKAVEANPNWRCFRC 236
            :.|.||..  ....|..|..|...||..|..|::.:    ....:|.|..|
Mouse   342 KCCNLCGTSENDDQLLFCDDCDRGYHMYCLTPSMSE----PPEGSWSCHLC 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2662	NP_001284832.1	PHD	134..187	CDD:214584	14/56 (25%)
		PHD	189..236	CDD:214584	12/48 (25%)
		SAM_Atherin-like	371..438	CDD:188982
		SAM	371..436	CDD:197735
Dpf2	NP_001278007.1	Requiem_N	13..79	CDD:290758
		PHD1_DPF2_like	286..341	CDD:277161	14/58 (24%)
		PHD2_d4	343..388	CDD:277005	12/48 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3744
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.860