DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spg7 and RPT1

DIOPT Version :10

Sequence 1:NP_570017.1 Gene:Spg7 / 31253 FlyBaseID:FBgn0024992 Length:819 Species:Drosophila melanogaster
Sequence 2:NP_012777.1 Gene:RPT1 / 853712 SGDID:S000001628 Length:467 Species:Saccharomyces cerevisiae


Alignment Length:452 Identity:124/452 - (27%)
Similarity:206/452 - (45%) Gaps:92/452 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   222 RPDMEMVTIILHEGAVIKGRKVSSTIFHMAVADANKFEEKLRDVEKRLGIKDGV----------- 275
            :||.:.: :.|.||.:...:...:..:   .|...:.|..|:|:|.|:..|.||           
Yeast    20 KPDDDKI-VPLTEGDIQVLKSYGAAPY---AAKLKQTENDLKDIEARIKEKAGVKESDTGLAPSH 80

  Fly   276 --PVTYDRQ---------------------------TDTTGR----------------------- 288
              .:..|||                           ||....                       
Yeast    81 LWDIMGDRQRLGEEHPLQVARCTKIIKGNGESDETTTDNNNSGNSNSNSNQQSTDADEDDEDAKY 145

  Fly   289 ILMLLLVCALLMSIATRMKSIKSPLSMDSFNQMG--RAKFTL-------VDP------FDGGRGV 338
            ::.|..:...::.:..|:    ||..::...::|  |:|:.:       :||      .:....|
Yeast   146 VINLKQIAKFVVGLGERV----SPTDIEEGMRVGVDRSKYNIELPLPPRIDPSVTMMTVEEKPDV 206

  Fly   339 LFRDVAGLSEAKQEVKEFVDY-LKSPEKYQRLGAKVPRGALLLGPPGCGKTLLAKAVATEAQVPF 402
            .:.||.|..:..::::|.|:. |.|||::..||...|:|.||.||||.||||.|:|||......|
Yeast   207 TYSDVGGCKDQIEKLREVVELPLLSPERFATLGIDPPKGILLYGPPGTGKTLCARAVANRTDATF 271

  Fly   403 LSMNGSEFIEMIGGLGAARVRDLFKEGKKRAPCIIYIDEIDAIGRQRSGTESMGQGSSGESEQTL 467
            :.:.|||.::...|.||..||:||:..:.:..|||:.|||||:|..|...   |.|...|.::|:
Yeast   272 IRVIGSELVQKYVGEGARMVRELFEMARTKKACIIFFDEIDAVGGARFDD---GAGGDNEVQRTM 333

  Fly   468 NQLLVEMDGMATKEGVLMLASTNRADILDKALLRPGRFDRHILIDLPTLAERKEIFEKHLSSVKL 532
            .:|:.::||...:..:.::.:|||.:.||.|||||||.||.:...||.|..|..||..|..|:.:
Yeast   334 LELITQLDGFDPRGNIKVMFATNRPNTLDPALLRPGRIDRKVEFSLPDLEGRANIFRIHSKSMSV 398

  Fly   533 ESPPTTFSQRLARLTPGFSGADIANVCNEAALHAARNTQMEVSSKNLEYAVERLVGGTEKRS 594
            |.....  :.::||.|..:||::.:||.||.:.|.|..:...:.|:...||::::.|.:|.|
Yeast   399 ERGIRW--ELISRLCPNSTGAELRSVCTEAGMFAIRARRKVATEKDFLKAVDKVISGYKKFS 458

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spg7NP_570017.1 HflB 178..788 CDD:440233 124/452 (27%)
RPT1NP_012777.1 PRK03992 154..466 CDD:179699 104/314 (33%)

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