Protein Alignment Spg7 and RPT3

DIOPT Version :10

• Sequence 1: NP_570017.1
• Gene: Spg7 / 31253
• FlyBaseID: FBgn0024992
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_010682.3
• Gene: RPT3 / 852003
• SGDID: S000002802
• Length: 428
• Species: Saccharomyces cerevisiae
• Alignment Length: 341
• Identity: 121/341 - (35%)
• Similarity: 174/341 - (51%)
• Gaps: 44/341 - (12%)

  Fly   262 LRDVEKRLGIKDGVPVTYDRQTDTTGRILMLLLVCAL-------LMSIATRMKS-----IKSPLS 314
            |..:::..||          .:.|||...::.::..|       .||:|....|     |..|.|
Yeast   100 LEPIDQNTGI----------VSSTTGMSYVVRILSTLDRELLKPSMSVALHRHSNALVDILPPDS 154

  Fly   315 MDSFNQMGRAKFTLVDPFDGGRGVLFRDVAGLSEAKQEVKEFVDY-LKSPEKYQRLGAKVPRGAL 378
            ..|.:.||..:    .|     .|.:.||.||...|||::|.|:. |...:.|:::|...|||.|
Yeast   155 DSSISVMGENE----KP-----DVTYADVGGLDMQKQEIREAVELPLVQADLYEQIGIDPPRGVL 210

  Fly   379 LLGPPGCGKTLLAKAVATEAQVPFLSMNGSEFIEMIGGLGAARVRDLFKEGKKRAPCIIYIDEID 443
            |.||||.|||:|.||||...:..|:.:|||||:....|.|...|||:|:..::.||.||:|||:|
Yeast   211 LYGPPGTGKTMLVKAVANSTKAAFIRVNGSEFVHKYLGEGPRMVRDVFRLARENAPSIIFIDEVD 275

  Fly   444 AIGRQRSGTESMGQGSSGESEQTLNQLLVEMDGMATKEGVLMLASTNRADILDKALLRPGRFDRH 508
            :|..:|...::   ||..|.::.|.:||.:|||......|.::.:|||||.||.|||||||.||.
Yeast   276 SIATKRFDAQT---GSDREVQRILIELLTQMDGFDQSTNVKVIMATNRADTLDPALLRPGRLDRK 337

  Fly   509 ILIDLPTLAERKE---IFEKHLSSVKLESPPTTFSQRLARLTPGFSGADIANVCNEAALHAARNT 570
              |:.|:|.:|:|   ||....|.:.| :|.......:.| ....|||.||.:..||.|.|.|..
Yeast   338 --IEFPSLRDRRERRLIFGTIASKMSL-APEADLDSLIIR-NDSLSGAVIAAIMQEAGLRAVRKN 398

  Fly   571 QMEVSSKNLE--YAVE 584
            :..:...:||  ||.:
Yeast   399 RYVILQSDLEEAYATQ 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spg7	NP_570017.1	HflB	178..788	CDD:440233	121/341 (35%)
RPT3	NP_010682.3	PTZ00454	46..428	CDD:240423	121/341 (35%)