Protein Alignment Spg7 and BCS1

DIOPT Version :10

• Sequence 1: NP_570017.1
• Gene: Spg7 / 31253
• FlyBaseID: FBgn0024992
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_010663.1
• Gene: BCS1 / 851981
• SGDID: S000002783
• Length: 456
• Species: Saccharomyces cerevisiae
• Alignment Length: 557
• Identity: 132/557 - (23%)
• Similarity: 203/557 - (36%)
• Gaps: 155/557 - (27%)

  Fly    65 QLTPKEVRLMHLRSLSSTAKPPTASDGKTEKHEQPEKGSAKAKDDSSKEKKSAVAAEDGDKSSR- 128
            |.||         :||....|||...|                :||.:||.|.:.   ||..|.
Yeast    13 QATP---------NLSGVITPPTNETG----------------NDSVREKLSKLV---GDAMSNN 49

  Fly   129 ---AAGEEAASTPTSSSTIGEPGEDPNKNSNENDEKMRSVLTKAVLWLFTIYMFVAF-------- 182
               |||.......|..:.                  .||.:.||...|:. .|.|..
Yeast    50 PYFAAGGGLMILGTGLAV------------------ARSGIIKASRVLYR-QMIVDLEIQSKDKS 95

  Fly   183 FSLLITPRSERPEGSTRYVS--WNEFVHHMLAVGEVKELIIRPDMEMVTIILHEGAVIKGRKVSS 245
            ::..:|..::.|:..:|::|  .|...|...:|.....|:..|....   |.::||.|..::..|
Yeast    96 YAWFLTWMAKHPQRVSRHLSVRTNYIQHDNGSVSTKFSLVPGPGNHW---IRYKGAFILIKRERS 157

  Fly   246 TIFHMAVADANKFEEKLRDVEKRLGIKDGVPVTYDRQTDTTGRILMLLLVCALLMSIATRMKSIK 310
            .                    |.:.|.:|.|  ::..|.||     |.....|...|....|.|.
Yeast   158 A--------------------KMIDIANGSP--FETVTLTT-----LYRDKHLFDDILNEAKDIA 195

  Fly   311 ------SPLSMDSF----NQMGRAKFTLVDP---FDGG--RGVLFRDVAGLSEAKQEVKEFVDYL 360
                  ..:...||    .:.|:.|...:.|   .|.|  .|:|              .:..|::
Yeast   196 LKTTEGKTVIYTSFGPEWRKFGQPKAKRMLPSVILDSGIKEGIL--------------DDVYDFM 246

  Fly   361 KSPEKYQRLGAKVPRGALLLGPPGCGKTLLAKAVATEAQVPFLSMNGSEFIEMIGGLGAARVRDL 425
            |:.:.|...|....||.||.||||.|||...:|:|.|.......:|.||     ..|...|:..|
Yeast   247 KNGKWYSDRGIPYRRGYLLYGPPGSGKTSFIQALAGELDYNICILNLSE-----NNLTDDRLNHL 306

  Fly   426 FKEGKKRAPCIIYIDEIDAIGRQRSGTESMGQGSSGESEQTLNQLLVEMDGMATKEGVLMLASTN 490
            .....:|:  |:.:::|||...:||.|...|..||    .|.:.||..:||:.:.|..:...:||
Yeast   307 MNNMPERS--ILLLEDIDAAFNKRSQTGEQGFHSS----VTFSGLLNALDGVTSSEETITFMTTN 365

  Fly   491 RADILDKALLRPGRFDRHILIDLPTLAERKEIF-----------EKHLSSVKLESPPTTFSQRLA 544
            ..:.||.|::||||.|..:.:...|..:.:::|           :|.::||| |...|..:.:|.
Yeast   366 HPEKLDAAIMRPGRIDYKVFVGNATPYQVEKMFMKFYPGETDICKKFVNSVK-ELDITVSTAQLQ 429

  Fly   545 RLTPGFSGADIANVCNEAALHAARNTQMEVSSKNLEY 581
            .|.          |.|:.|.|.|  .:|..|.:|..:
Yeast   430 GLF----------VMNKDAPHDA--LKMVSSLRNANH 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spg7	NP_570017.1	HflB	178..788	CDD:440233	106/440 (24%)
BCS1	NP_010663.1	BCS1_N	59..228	CDD:214980	39/217 (18%)
		RecA-like_BCS1	238..386	CDD:410918	52/172 (30%)