Protein Alignment Spg7 and VAR1

DIOPT Version :10

• Sequence 1: NP_570017.1
• Gene: Spg7 / 31253
• FlyBaseID: FBgn0024992
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_568604.1
• Gene: VAR1 / 834232
• AraportID: AT5G42270
• Length: 704
• Species: Arabidopsis thaliana
• Alignment Length: 795
• Identity: 270/795 - (33%)
• Similarity: 408/795 - (51%)
• Gaps: 143/795 - (17%)

  Fly    16 GSQLIQLRSATGQPPRIGRELSLLQLSRRQVMQLQAEYKAIVGLIARSLQLTPKEVRLMHLRSLS 80
            |||:| :.:.|.:........|::...|.|:.|.:...|::           |.:..|..|  |.
plant    17 GSQII-ISAPTPKTTTKSLPFSVISRKRYQISQSEKLMKSL-----------PSQAALAAL--LF 67

  Fly    81 STAKPPTASDGKTEKHEQPEKGSAKAKDDSSKEKKSAVAAEDGDKSSRAAGEEAASTPTSSSTIG 145
            |::.|                 .|.|.::..:.....:.||....:....|:....|.
plant    68 SSSSP-----------------QALAVNEPVQPPAPTITAEAQSPNLSTFGQNVLMTA------- 108

  Fly   146 EPGEDPNKNSNENDEKMRSVLTKAVLWLFTIYMFVAFFSLLITPRSER----PEGSTRYVSWNEF 206
                 ||..:..:|      |.....|.::     .|.:.:...:.||    .:||
plant   109 -----PNPQAQSSD------LPDGTQWRYS-----EFLNAVKKGKVERVKFSKDGS--------- 148

  Fly   207 VHHMLAVGEVKELIIRP-DMEMVTIILHEGAVIKGRKVSSTIFHMAVADANKFEEKLRDVEKRLG 270
            |..:.||...:..:|.| |.:::.|:...|..|                      .:.:.|...|
plant   149 VLQLTAVDNRRATVIVPNDPDLIDILAMNGVDI----------------------SVSEGEGGNG 191

  Fly   271 IKDGVPVTYDRQTDTTGRILMLLLVCALLMSI-------ATRMKSIKSPLSMDSFNQMGRAKFTL 328
            :.|.:           |.:|..||....|..:       |.....:..|:      ..||:|...
plant   192 LFDFI-----------GNLLFPLLAFGGLFYLFRGGQGGAGGPGGLGGPM------DFGRSKSKF 239

  Fly   329 VDPFDGGRGVLFRDVAGLSEAKQEVKEFVDYLKSPEKYQRLGAKVPRGALLLGPPGCGKTLLAKA 393
            .:..:  .||.|.||||..:||.|::|.||:||:|:||..||||:|:|.||:||||.||||||:|
plant   240 QEVPE--TGVTFGDVAGADQAKLELQEVVDFLKNPDKYTALGAKIPKGCLLVGPPGTGKTLLARA 302

  Fly   394 VATEAQVPFLSMNGSEFIEMIGGLGAARVRDLFKEGKKRAPCIIYIDEIDAIGRQRSGTESMGQG 458
            ||.||.|||.|...|||:|:..|:||:||||||::.|.:||||::||||||:||||..  .|| |
plant   303 VAGEAGVPFFSCAASEFVELFVGVGASRVRDLFEKAKSKAPCIVFIDEIDAVGRQRGA--GMG-G 364

  Fly   459 SSGESEQTLNQLLVEMDGMATKEGVLMLASTNRADILDKALLRPGRFDRHILIDLPTLAERKEIF 523
            .:.|.|||:||||.||||.:...||::||:|||.|:||.||||||||||.:.:|.|.:|.|.:|.
plant   365 GNDEREQTINQLLTEMDGFSGNSGVIVLAATNRPDVLDSALLRPGRFDRQVTVDRPDVAGRVQIL 429

  Fly   524 EKHLSSVKLESPPTTFSQRLARLTPGFSGADIANVCNEAALHAARNTQMEVSSKNLEYAVERLVG 588
            :.| |..|.......: :::||.||||:|||:.|:.||||:.|||....|:|...:..|:||::.
plant   430 KVH-SRGKAIGKDVDY-EKVARRTPGFTGADLQNLMNEAAILAARRELKEISKDEISDALERIIA 492

  Fly   589 GTEKRSHALSLAERKVIAYHESGHALVGWMLPNSDILLKVTIVPRTSLALGFAQYTPSEQH---- 649
            |.||::..:|..:::::||||:||||||.::|..|.:.|::|:|| ..|.|...:.|||:.
plant   493 GPEKKNAVVSEEKKRLVAYHEAGHALVGALMPEYDPVAKISIIPR-GQAGGLTFFAPSEERLESG 556

  Fly   650 LYSKEELFDKMCMALGGRAAENLVF--NRITTGAQNDLEKVTKIAYSQIKKFGMNDTLGPIYVRD 712
            |||:..|.::|.:|||||.||.::|  ..:||||.||..:|:::|...:::||.:..:|.:.|
plant   557 LYSRSYLENQMAVALGGRVAEEVIFGDENVTTGASNDFMQVSRVARQMVERFGFSKKIGQVAV-- 619

  Fly   713 ADETEGGGAMGS-------GGKKPFSRAMESMIDNEARHVVASAYQTTEGILTTHRDKLEKLAEA 770
                  |||.|:       ..:|.:|.|...::|.|.|.:|..||...:.|:||..|.|.|||:.
plant   620 ------GGAGGNPFLGQSMSSQKDYSMATADVVDAEVRELVEKAYVRAKEIITTQIDILHKLAQL 678

  Fly   771 LLEKETLDYDQVVQL 785
            |:||||:|.::.:.|
plant   679 LIEKETVDGEEFMSL 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spg7	NP_570017.1	HflB	178..788	CDD:440233	243/633 (38%)
VAR1	NP_568604.1	HflB	104..694	CDD:440233	249/677 (37%)