DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spg7 and Bcs1l

DIOPT Version :9

Sequence 1:	NP_570017.1	Gene:	Spg7 / 31253	FlyBaseID:	FBgn0024992	Length:	819	Species:	Drosophila melanogaster
Sequence 2:	NP_001292581.1	Gene:	Bcs1l / 66821	MGIID:	1914071	Length:	418	Species:	Mus musculus

Alignment Length:	206	Identity:	58/206 - (28%)
Similarity:	91/206 - (44%)	Gaps:	35/206 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   351 QEVKEFVDYLKSPEKYQRLGAKVPRGALLLGPPGCGKTLLAKAVATEAQ--VPFLSMNGSEFIEM 413
            ::::||:|   :|:.|...|....||.||.|||||||:....|:|.|.:  :..||:..|
Mouse   203 KDIREFID---NPKWYIDRGIPYRRGYLLYGPPGCGKSSFITALAGELEHSICLLSLTDS----- 259

  Fly   414 IGGLGAARVRDLFKEGKKRAPCIIYIDEIDAIGRQRSGTESMGQGSSGESEQTLNQLLVEMDGMA 478
              .|...|:..|.....:::  ::.::::||....|...........|....|.:.||..:||:|
Mouse   260 --SLSDDRLNHLLSVAPQQS--LVLLEDVDAAFLSRDLAVENPIKYQGLGRLTFSGLLNALDGVA 320

  Fly   479 TKEGVLMLASTNRADILDKALLRPGR------------------FDRHILIDLPTLAERKEIFEK 525
            :.|..::..:||..|.||.||:||||                  |.|......|:|||.   |.:
Mouse   321 STEARIVFMTTNYIDRLDPALIRPGRVDLKEYVGYCSHWQLTQMFQRFYPGQAPSLAEN---FAE 382

  Fly   526 HLSSVKLESPP 536
            |:.....|..|
Mouse   383 HVLKATSEISP 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spg7	NP_570017.1	FtsH_ext	171..276	CDD:284011
		FtsH_fam	333..787	CDD:273520	58/206 (28%)
		AAA	378..513	CDD:278434	42/154 (27%)
		Peptidase_M41	595..785	CDD:279742
Bcs1l	NP_001292581.1	BCS1_N	24..191	CDD:214980
		AAA	223..354	CDD:214640	42/139 (30%)
		AAA	226..355	CDD:278434	40/137 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0465
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810