DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spg7 and Bcs1l

DIOPT Version :9

Sequence 1:	NP_570017.1	Gene:	Spg7 / 31253	FlyBaseID:	FBgn0024992	Length:	819	Species:	Drosophila melanogaster
Sequence 2:	NP_001007667.1	Gene:	Bcs1l / 301514	RGDID:	1359658	Length:	418	Species:	Rattus norvegicus

Alignment Length:	207	Identity:	55/207 - (26%)
Similarity:	98/207 - (47%)	Gaps:	15/207 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   351 QEVKEFVDYLKSPEKYQRLGAKVPRGALLLGPPGCGKTLLAKAVATEAQ--VPFLSMNGSEFIEM 413
            ::::||:|   :|:.|...|....||.||.|||||||:....|:|.|.:  :..||:..|
  Rat   203 KDIREFID---NPKWYIDRGIPYRRGYLLYGPPGCGKSSFITALAGELEHSICLLSLTDS----- 259

  Fly   414 IGGLGAARVRDLFKEGKKRAPCIIYIDEIDAIGRQRSGTESMGQGSSGESEQTLNQLLVEMDGMA 478
              .|...|:..|.....:::  ::.::::||....|...........|....|.:.||..:||:|
  Rat   260 --SLSDDRLNHLLSVAPQQS--LVLLEDVDAAFLSRDLAVENPVKYQGLGRLTFSGLLNALDGVA 320

  Fly   479 TKEGVLMLASTNRADILDKALLRPGRFDRHILIDLPTLAERKEIFEKHLSSVKLESPPTTFSQRL 543
            :.|..::..:||..|.||.||:||||.|....:...:..:..::|::.... :..|....|::.:
  Rat   321 STEARIVFMTTNHIDRLDPALIRPGRVDLKEYVGYCSHWQLTQMFQRFYPG-QAPSLAENFAEHV 384

  Fly   544 ARLTPGFSGADI 555
            .:.|...|.|.:
  Rat   385 LKATSQISPAQV 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spg7	NP_570017.1	FtsH_ext	171..276	CDD:284011
		FtsH_fam	333..787	CDD:273520	55/207 (27%)
		AAA	378..513	CDD:278434	41/136 (30%)
		Peptidase_M41	595..785	CDD:279742
Bcs1l	NP_001007667.1	BCS1_N	24..191	CDD:214980
Bcs1l	NP_001007667.1	RecA-like_BCS1	201..353	CDD:410918	49/161 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0465
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810