Protein Alignment Spg7 and Bcs1

DIOPT Version :10

• Sequence 1: NP_570017.1
• Gene: Spg7 / 31253
• FlyBaseID: FBgn0024992
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: XP_313188.3
• Gene: Bcs1 / 1274111
• VectorBaseID: AGAMI1_001322
• Length: 424
• Species: Anopheles gambiae
• Alignment Length: 391
• Identity: 99/391 - (25%)
• Similarity: 159/391 - (40%)
• Gaps: 99/391 - (25%)

  Fly   188 TPRSERPEG--STRYVSWNEFV----HHMLAVGEVKELIIRPDMEMVTIILHEGAVIKGRKVSST 246
            |...:|..|  .|||    :|:    .|::..|.....:.|. .|..|:.||.|  :....|..|
Mosquito    82 TSFEQRDTGHIKTRY----DFIPSVGTHIMRYGGTWIKVDRA-REQHTLDLHMG--VPWETVQLT 139

  Fly   247 IFHMAVADANKFEEKLRDVEKRLGIKDGVPVTYDRQTDTTGRILMLLLVCALLMSIATRMKSIKS 311
            .|.   .|.|.: .|:.:..::|.:|           :|.|:.:|
Mosquito   140 AFG---RDKNLY-FKILEEARQLALK-----------NTEGKTIM-------------------- 169

  Fly   312 PLSMDSFNQMGRAKFTLVDPFDGGR-----GVLFRDVAGLSEAKQEVKEFVDYLKSPEKYQRLGA 371
                  :..||    :...||...|     |.:..| .|:||  :.:::..:::|:|:.|...|.
Mosquito   170 ------YTAMG----SEWRPFGHPRKRRPIGSVVLD-EGVSE--RILRDCREFIKNPQWYSDRGI 221

  Fly   372 KVPRGALLLGPPGCGKTLLAKAVATEAQVPFLSMNGSEFIEMIGGLGAARVRDLFKEGKKRAPCI 436
            ...||.||.|||||||:....|:|.|.:.....:|.||     .||...|:..|.....:::  |
Mosquito   222 PYRRGYLLHGPPGCGKSSFITALAGEIEFGICLLNLSE-----RGLTDDRLNHLMNVAPQQS--I 279

  Fly   437 IYIDEIDAIGRQRSGTESMGQGSSGESEQTLNQLLVEMDGMATKEGVLMLASTNRADILDKALLR 501
            |.:::|||....|..|........|.:..|.:.||..:||:|:.|..::..:||..:.||.||:|
Mosquito   280 ILLEDIDAAFVSRQDTLQQKAAYEGLNRVTFSGLLNCLDGVASTEARIVFMTTNYLERLDPALIR 344

  Fly   502 PGRFD---------RHILIDLPTLAERKEIFEKHLSSVKLESPPTTFSQRLARLTPGFSGADIAN 557
            |||.|         ||.|         :::|.:..:....|:....|::|:|        ||..|
Mosquito   345 PGRVDVKEYVGHCSRHQL---------EQMFRRFYTGTDAEANARIFAERVA--------ADGRN 392

  Fly   558 V 558
            |
Mosquito   393 V 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spg7	NP_570017.1	HflB	178..788	CDD:440233	99/391 (25%)
Bcs1	XP_313188.3	BCS1_N	23..192	CDD:214980	32/161 (20%)
		RecA-like_BCS1	202..354	CDD:410918	51/158 (32%)