Protein Alignment Spg7 and Psmc1

DIOPT Version :10

• Sequence 1: NP_570017.1
• Gene: Spg7 / 31253
• FlyBaseID: FBgn0024992
• Length: 819
• Species: Drosophila melanogaster
• Sequence 2: NP_476464.1
• Gene: Psmc1 / 117263
• RGDID: 621097
• Length: 440
• Species: Rattus norvegicus
• Alignment Length: 505
• Identity: 150/505 - (29%)
• Similarity: 228/505 - (45%)
• Gaps: 108/505 - (21%)

  Fly   102 GSAKAKDDSSKEKK--SAVAAEDGDKSSRAAGEEAAS-----TPTSSSTIG----EPGEDPNKNS 155
            |..| |||..|:||  ..|....|.|..:..|.:|||     ||.:...:.    |..:|.....
  Rat    12 GGGK-KDDKDKKKKYEPPVPTRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLLME 75

  Fly   156 NE---NDEKMRSVLTKAVLWLFTIYMFVAFFSLLITPRSERPEGSTRYVSWNEFVHHMLAVGEVK 217
            .|   |.|:|:                         |..|:.|.....|  ::.....::||.::
  Rat    76 EEFIRNQEQMK-------------------------PLEEKQEEERSKV--DDLRGTPMSVGTLE 113

  Fly   218 ELIIRPDMEMVTIILHEGAVIKGRKVSSTIFHMAVADANKFEEKLRDVEKRLGIKDGVPVTYDRQ 282
            |:|  .|...:              ||:::      .:..:...|..|:|.| ::.|..|..:.:
  Rat   114 EII--DDNHAI--------------VSTSV------GSEHYVSILSFVDKDL-LEPGCSVLLNHK 155

  Fly   283 TDTTGRILMLLLVCALLMS----IATRMKSIKSPLSMDSFNQMGRAKFTLVDPFDGGRGVLFRDV 343
            ...         |..:||.    :.|.||..|:|..                        .:.|:
  Rat   156 VHA---------VIGVLMDDTDPLVTVMKVEKAPQE------------------------TYADI 187

  Fly   344 AGLSEAKQEVKEFVDY-LKSPEKYQRLGAKVPRGALLLGPPGCGKTLLAKAVATEAQVPFLSMNG 407
            .||....||:||.|:. |..||.|:.:|.|.|:|.:|.||||.||||||||||.:....||.:.|
  Rat   188 GGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVG 252

  Fly   408 SEFIEMIGGLGAARVRDLFKEGKKRAPCIIYIDEIDAIGRQRSGTESMGQGSSGESEQTLNQLLV 472
            ||.|:...|.|...||:||:..::.||.|::||||||||.:|..:.|   |...|.::|:.:||.
  Rat   253 SELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNS---GGEREIQRTMLELLN 314

  Fly   473 EMDGMATKEGVLMLASTNRADILDKALLRPGRFDRHILIDLPTLAERKEIFEKHLSSVKLESPPT 537
            ::||..::..|.::.:|||.:.||.||:||||.||.|...||....:|.||:.|.|.:.|....|
  Rat   315 QLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVT 379

  Fly   538 TFSQRLARLTPGFSGADIANVCNEAALHAARNTQMEVSSKNLEYAVERLV 587
            .....:|:  ...|||||..:|.||.|.|.|..:|:|::::.:.:.|.::
  Rat   380 LDDLIMAK--DDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVL 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spg7	NP_570017.1	HflB	178..788	CDD:440233	127/415 (31%)
Psmc1	NP_476464.1	PTZ00361	1..440	CDD:185575	150/505 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..49		15/37 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	84..104		5/46 (11%)