Protein Alignment HLH3B and HAND2

DIOPT Version :10

• Sequence 1: NP_525055.1
• Gene: HLH3B / 31249
• FlyBaseID: FBgn0011276
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_068808.1
• Gene: HAND2 / 9464
• HGNCID: 4808
• Length: 217
• Species: Homo sapiens
• Alignment Length: 149
• Identity: 48/149 - (32%)
• Similarity: 70/149 - (46%)
• Gaps: 17/149 - (11%)

  Fly   107 ADANRSLSSSPRSHSRN-----GLLTAP---------ASSGSSVGGSGGGGGNGS--GGNASSGG 155
            |.|..:.::|..||..|     .|:..|         |.|.|....||..|.:.|  ||.....|
Human    24 AAAAAAAAASRCSHEENPYFHGWLIGHPEMSPPDYSMALSYSPEYASGAAGLDHSHYGGVPPGAG 88

  Fly   156 GSGVGATGGVRKVFT-NTRERWRQQNVSGAFAELRKLVPTHPPDKKLSKNEILRSAIKYIKLLTG 219
            ..|:|....|::..| |.:||.|.|:::.||||||:.:|..|.|.||||.:.||.|..||..|..
Human    89 PPGLGGPRPVKRRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMD 153

  Fly   220 ILEWQQRQAPSHPIRAQME 238
            :|....:...:...:|:::
Human   154 LLAKDDQNGEAEAFKAEIK 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLH3B	NP_525055.1	bHLH_TS_dHLH3B_like	166..225	CDD:381551	26/59 (44%)
HAND2	NP_068808.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..116		13/39 (33%)
		bHLH_TS_HAND2	100..161	CDD:381477	26/60 (43%)