Protein Alignment HLH3B and ATOH8

DIOPT Version :10

• Sequence 1: NP_525055.1
• Gene: HLH3B / 31249
• FlyBaseID: FBgn0011276
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: XP_011531441.1
• Gene: ATOH8 / 84913
• HGNCID: 24126
• Length: 328
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 70/276 - (25%)
• Similarity: 95/276 - (34%)
• Gaps: 67/276 - (24%)

  Fly    10 GADNADERSTASSGSSGHSQTNESPRSGHLNGNGSMRDTAAGRHPPALLRHATPHLQPKTESISD 74
            |.|.|.||     |.|...:.:::.:          |..|.|...|.|   .||...|.....|.
Human    89 GTDTAGER-----GGSRAPEVSDARK----------RCFALGAVGPGL---PTPPPPPPPAPQSQ 135

  Fly    75 GDGDAELSDFSLNDTEEDEEDLRDYIVLNGNQADANRSLSSSPRSHSRNGLLTAP-----ASSGS 134
            ..|..|...|.       |..||..|:|....|....|...:|.:...:.:..||     .||.|
Human   136 APGGPEAQPFR-------EPGLRPRILLCAPPARPAPSAPPAPPAPPESTVRPAPPTRPGESSYS 193

  Fly   135 SVGGSGGGGGNGSGGNASSGGGSGVGATGGV------RKVFTNTRERWRQQNVSGAFAELRKLVP 193
            |:..........|..:.....|....|:..:      |::..|.|||.|...:|.||..|||.||
Human   194 SISHVIYNNHQDSSASPRKRPGEATAASSEIKALQQTRRLLANARERTRVHTISAAFEALRKQVP 258

  Fly   194 THPPDKKLSKNEILRSAIKYIKLLTGILEWQQRQAPSHPIRAQMEPNNNDNRMAN-GHAADGENL 257
            .:...:||||..|||.|..||..|.                          |:|: .::||..||
Human   259 CYSYGQKLSKLAILRIACNYILSLA--------------------------RLADLDYSADHSNL 297

  Fly   258 ENPDVPPVRHIKCERT 273
            ...:...    :|.||
Human   298 SFSECVQ----RCTRT 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLH3B	NP_525055.1	bHLH_TS_dHLH3B_like	166..225	CDD:381551	25/58 (43%)
ATOH8	XP_011531441.1	bHLH_TS_ATOH8	224..291	CDD:381427	27/92 (29%)