Protein Alignment HLH3B and MESP1

DIOPT Version :10

• Sequence 1: NP_525055.1
• Gene: HLH3B / 31249
• FlyBaseID: FBgn0011276
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_061140.1
• Gene: MESP1 / 55897
• HGNCID: 29658
• Length: 268
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 71/266 - (26%)
• Similarity: 99/266 - (37%)
• Gaps: 79/266 - (29%)

  Fly   108 DANRSLSSSP------------RSHSRNGLLTAPASSGSSVGGSGGGGGNGSGGNASSGGGSGVG 160
            |..|||.|||            .|.:|.|.|..|.:  .|||..|.         .||..|||
Human    31 DCGRSLVSSPDSWGSTPADSPVASPARPGTLRDPRA--PSVGRRGA---------RSSRLGSG-- 82

  Fly   161 ATGGVRKVFTNTRERWRQQNVSGAFAELRKLVP--THPPDKKLSKNEILRSAIKYIKLLTGIL-- 221
                 ::...:.||:.|.:.::.|..|||:.:|  ..|..:.|:|.|.||.||:||..|:.:|
Human    83 -----QRQSASEREKLRMRTLARALHELRRFLPPSVAPAGQSLTKIETLRLAIRYIGHLSAVLGL 142

  Fly   222 -------EWQQRQAPSHPIRAQMEPNNNDNRMANGHAADGENLENPDVPPVRHIKCERTDGQMHR 279
                   ..:||.....|....:.|::...:|.....|:|:                   ||
Human   143 SEESLQRRCRQRGDAGSPRGCPLCPDDCPAQMQTRTQAEGQ-------------------GQ--- 185

  Fly   280 NGIGHG-----HANGNAGNDLLMIAPGAVVKSE------LLLESTLPLGHPLN-GPPLPLTTAP- 331
             |.|.|     .|..:.|:.  ...|||....|      |..|:..|.|..:. .||.||....
Human   186 -GRGLGLVSAVRAGASWGSP--PACPGARAAPEPRDPPALFAEAACPEGQAMEPSPPSPLLPGDV 247

  Fly   332 LAMAET 337
            ||:.||
Human   248 LALLET 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLH3B	NP_525055.1	bHLH_TS_dHLH3B_like	166..225	CDD:381551	20/69 (29%)
MESP1	NP_061140.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	17..93		23/79 (29%)
		bHLH_TS_Mesp	83..147	CDD:381508	20/63 (32%)
		CPLCP	163..167		0/3 (0%)
		2 X 2 AA tandem repeats of G-Q	182..185		1/21 (5%)