Protein Alignment HLH3B and Neurod2

DIOPT Version :10

• Sequence 1: NP_525055.1
• Gene: HLH3B / 31249
• FlyBaseID: FBgn0011276
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_062199.2
• Gene: Neurod2 / 54276
• RGDID: 3166
• Length: 382
• Species: Rattus norvegicus
• Alignment Length: 312
• Identity: 69/312 - (22%)
• Similarity: 110/312 - (35%)
• Gaps: 90/312 - (28%)

  Fly     4 LPSSSNGADNADERSTASSGSSGHSQTNESPRSGHLNGNGSMRDTAAGRHPPALLRHATPH---L 65
            :|..::..|..|:...:..|.: ..|...:|.||   ..|..|.|    .|.:|.....|.   .
  Rat    15 VPKFASWGDGDDDEPRSDKGDA-PPQPPPAPGSG---APGPARAT----KPVSLRGEEVPEPTLA 71

  Fly    66 QPKTESISDGDGDAELSDFSLNDTEEDEEDLRDYIVLNGNQADANRSLSSSPRSHSRNGLLTAPA 130
            :.|.|....|:.:.|         ||:||.|        ::|:..|.....|:...    :|...
  Rat    72 EVKEEGELGGEEEEE---------EEEEEGL--------DEAEGERPKKRGPKKRK----MTKAR 115

  Fly   131 SSGSSVGGSGGGGGNGSGGNASSGGGSGVGATGGVRKVFTNTRERWRQQNVSGAFAELRKLVPTH 195
            ...|.                             :|:...|.|||.|..:::.|...|||:||.:
  Rat   116 LERSK-----------------------------LRRQKANARERNRMHDLNAALDNLRKVVPCY 151

  Fly   196 PPDKKLSKNEILRSAIKYIKLLTGILEWQQR---------------QAPSHPIRAQMEPNNND-- 243
            ...:||||.|.||.|..||..|:.||...:|               |..::.:...::.|:.:
  Rat   152 SKTQKLSKIETLRLAKNYIWALSEILRSGKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLNSRNFL 216

  Fly   244 -NRMANG----HAADGENLENPDVPPVRHIKCERTDGQMHR--NGIGHGHAN 288
             .:.|:|    |.:.|....:|...|     |.|..|...:  .|:|.|.|:
  Rat   217 TEQGADGAGRFHGSGGPFAMHPYPYP-----CSRLAGAQCQAAGGLGGGAAH 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLH3B	NP_525055.1	bHLH_TS_dHLH3B_like	166..225	CDD:381551	25/58 (43%)
Neurod2	NP_062199.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..129		30/171 (18%)
		bHLH_TS_NeuroD2	88..180	CDD:381563	34/132 (26%)
		Nuclear localization signal. /evidence=ECO:0000255	107..113		0/9 (0%)
		Neuro_bHLH	180..310	CDD:463621	16/89 (18%)