Protein Alignment HLH3B and NEUROG3

DIOPT Version :10

• Sequence 1: NP_525055.1
• Gene: HLH3B / 31249
• FlyBaseID: FBgn0011276
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_066279.2
• Gene: NEUROG3 / 50674
• HGNCID: 13806
• Length: 214
• Species: Homo sapiens
• Alignment Length: 163
• Identity: 46/163 - (28%)
• Similarity: 66/163 - (40%)
• Gaps: 24/163 - (14%)

  Fly   115 SSPRSHSRNGLLTAPASSGSSVGGSGG-------GGGNGS--------GGNASSGGGSGVGATGG 164
            |.||:....  :|.|.|:..|...:.|       ||..|:        ||.:.......:.....
Human    20 SFPRASEDE--VTCPTSAPPSPTRTRGNCAEAEEGGCRGAPRKLRARRGGRSRPKSELALSKQRR 82

  Fly   165 VRKVFTNTRERWRQQNVSGAFAELRKLVPTHPPDKKLSKNEILRSAIKYIKLLTGILEWQQRQAP 229
            .|:...|.|||.|..|::.|...||.::||.|.|.||:|.|.||.|..||..||     |..:..
Human    83 SRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALT-----QTLRIA 142

  Fly   230 SHPIRAQMEPNNNDNRMAN--GHAADGENLENP 260
            .|.:.|...|..:...:.:  |...|..:|.:|
Human   143 DHSLYALEPPAPHCGELGSPGGSPGDWGSLYSP 175

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLH3B	NP_525055.1	bHLH_TS_dHLH3B_like	166..225	CDD:381551	25/58 (43%)
NEUROG3	NP_066279.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..98		19/79 (24%)
		bHLH_TS_NGN3_ATOH5	77..144	CDD:381561	26/71 (37%)