Protein Alignment HLH3B and NHLH2

DIOPT Version :10

• Sequence 1: NP_525055.1
• Gene: HLH3B / 31249
• FlyBaseID: FBgn0011276
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_005590.1
• Gene: NHLH2 / 4808
• HGNCID: 7818
• Length: 135
• Species: Homo sapiens
• Alignment Length: 135
• Identity: 50/135 - (37%)
• Similarity: 67/135 - (49%)
• Gaps: 13/135 - (9%)

  Fly   100 IVLNGNQ-ADANRSLSSSPRSHSRNGLLTAPASSGSSVGGSGGGGGNGSGGNASS---------- 153
            ::|:.:| ||::...|:.....|..|..|....|.|.:.......|:|.||:.::
Human     1 MMLSPDQAADSDHPSSAHSDPESLGGTDTKVLGSVSDLEPVEEAEGDGKGGSRAALYPHPQQLSR 65

  Fly   154 -GGGSGVGATGGVRKVFTNTRERWRQQNVSGAFAELRKLVPTHPPDKKLSKNEILRSAIKYIKLL 217
             .......||...|.... ||||.|.:..:.||||||||:||.||||||||.||||.||.||..|
Human    66 EEKRRRRRATAKYRSAHA-TRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYL 129

  Fly   218 TGILE 222
            ..:|:
Human   130 NHVLD 134

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLH3B	NP_525055.1	bHLH_TS_dHLH3B_like	166..225	CDD:381551	34/57 (60%)
NHLH2	NP_005590.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..80		16/78 (21%)
		bHLH_TS_HEN2	63..135	CDD:381545	36/73 (49%)