Protein Alignment HLH3B and NHLH1

DIOPT Version :10

• Sequence 1: NP_525055.1
• Gene: HLH3B / 31249
• FlyBaseID: FBgn0011276
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_005589.1
• Gene: NHLH1 / 4807
• HGNCID: 7817
• Length: 133
• Species: Homo sapiens
• Alignment Length: 130
• Identity: 52/130 - (40%)
• Similarity: 58/130 - (44%)
• Gaps: 34/130 - (26%)

  Fly   117 PRSHSRNGLLTAPASSGSSVGGSGGGGGNGSGGNASSGGGSGVG--------------------- 160
            |.:||..      .|..|..||..|..|.|.||   .|||...|
Human    13 PPTHSET------ESGFSDCGGGAGPDGAGPGG---PGGGQARGPEPGEPGRKDLQHLSREERRR 68

  Fly   161 ---ATGGVRKVFTNTRERWRQQNVSGAFAELRKLVPTHPPDKKLSKNEILRSAIKYIKLLTGILE 222
               ||...|.... ||||.|.:..:.||||||||:||.||||||||.||||.||.||..|..:|:
Human    69 RRRATAKYRTAHA-TRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLD 132

  Fly   223  222
            Human   133  132

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLH3B	NP_525055.1	bHLH_TS_dHLH3B_like	166..225	CDD:381551	34/57 (60%)
NHLH1	NP_005589.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..79		19/74 (26%)
		bHLH_TS_HEN1	61..132	CDD:381544	35/71 (49%)