Protein Alignment HLH3B and NEUROG1

DIOPT Version :10

• Sequence 1: NP_525055.1
• Gene: HLH3B / 31249
• FlyBaseID: FBgn0011276
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_006152.2
• Gene: NEUROG1 / 4762
• HGNCID: 7764
• Length: 237
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 58/265 - (21%)
• Similarity: 86/265 - (32%)
• Gaps: 87/265 - (32%)

  Fly    14 ADERSTASSGSSGHSQTNESPRSGHLNGN---GSMRDTAAGRHPPALLRHATPHLQPKTESISDG 75
            :|....:||||.         .||.|...   ..::..|:...|||..|...|::...:|
Human    10 SDLDCASSSGSD---------LSGFLTDEEDCARLQQAASASGPPAPARRGAPNISRASE----- 60

  Fly    76 DGDAELSDFSLNDTEEDEEDLRDYIVLNGNQADANRSLSSSPRSHSRNGLLTAPASSGSSVGGSG 140
                      :...::||::.|            .|...:..||.:   ||.:...|
Human    61 ----------VPGAQDDEQERR------------RRRGRTRVRSEA---LLHSLRRS-------- 92

  Fly   141 GGGGNGSGGNASSGGGSGVGATGGVRKVFTNTRERWRQQNVSGAFAELRKLVPTHPPDKKLSKNE 205
                                     |:|..|.|||.|..|::.|...||.::|:.|.|.||:|.|
Human    93 -------------------------RRVKANDRERNRMHNLNAALDALRSVLPSFPDDTKLTKIE 132

  Fly   206 ILRSAIKYIKLLTGILEWQQRQAPSHPIRAQMEPNN------------NDNRMANGHAADGENLE 258
            .||.|..||..|...|....:..|....|.::.|..            :|.......||....|.
Human   133 TLRFAYNYIWALAETLRLADQGLPGGGARERLLPPQCVPCLPGPPSPASDAESWGSGAAAASPLS 197

  Fly   259 NPDVP 263
            :|..|
Human   198 DPSSP 202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLH3B	NP_525055.1	bHLH_TS_dHLH3B_like	166..225	CDD:381551	25/58 (43%)
NEUROG1	NP_006152.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	35..83		12/74 (16%)
		bHLH_TS_NGN1_NeuroD3	82..153	CDD:381559	29/106 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	175..209		6/28 (21%)