DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment HLH3B and MSGN1

DIOPT Version :9

Sequence 1:	NP_525055.1	Gene:	HLH3B / 31249	FlyBaseID:	FBgn0011276	Length:	376	Species:	Drosophila melanogaster
Sequence 2:	NP_001099039.1	Gene:	MSGN1 / 343930	HGNCID:	14907	Length:	193	Species:	Homo sapiens

Alignment Length:	185	Identity:	50/185 - (27%)
Similarity:	74/185 - (40%)	Gaps:	46/185 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 SISDGDGDAE----LSDFSLNDTEEDEEDLRDYIVLNGNQADANRSLSSSP--RSHSRNGLLTAP 129
            |:.||.|.::    ||.:...|.....|         .|||..::|||.:|  .|:|.:   ..|
Human    10 SLEDGLGSSDSPGLLSSWDWKDRAGPFE---------LNQASPSQSLSPAPSLESYSSS---PCP 62

  Fly   130 ASSG--SSVGGSGGGGGNGSGGNASSG-----------------GGSGVGATGGV-------RKV 168
            |.:|  ...||:..||..|.....:||                 ||.|..|..|.       |:.
Human    63 AVAGLPCEHGGASSGGSEGCSVGGASGLVEVDYNMLAFQPTHLQGGGGPKAQKGTKVRMSVQRRR 127

  Fly   169 FTNTRERWRQQNVSGAFAELRKLVPT--HPPDKKLSKNEILRSAIKYIKLLTGIL 221
            ..:.||:.|.:.::.|...||..:|.  ....:.|:|.:.|:..||||..||.:|
Human   128 KASEREKLRMRTLADALHTLRNYLPPVYSQRGQPLTKIQTLKYTIKYIGELTDLL 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HLH3B	NP_525055.1	HLH	171..222	CDD:197674	17/53 (32%)
MSGN1	NP_001099039.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	34..59		10/33 (30%)
MSGN1	NP_001099039.1	HLH	125..179	CDD:278439	15/53 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810