Protein Alignment HLH3B and atoh1a

DIOPT Version :10

• Sequence 1: NP_525055.1
• Gene: HLH3B / 31249
• FlyBaseID: FBgn0011276
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_571166.2
• Gene: atoh1a / 30303
• ZFINID: ZDB-GENE-990415-17
• Length: 292
• Species: Danio rerio
• Alignment Length: 328
• Identity: 84/328 - (25%)
• Similarity: 112/328 - (34%)
• Gaps: 85/328 - (25%)

  Fly    88 DTEEDEE-DLRDYIVLNGNQADANRSL----SSSPRSHSRNGLLTAPASSGS----------SVG 137
            ||.|..| |::...:..|.|::...:|    ||.||:      ..||..:|:          |.|
Zfish     7 DTREVVELDVQHSSLGRGEQSEYPPALALMASSDPRA------WLAPVQAGTCAAHAEYLLHSPG 65

  Fly   138 GSGGGGGNGSGGNASSGG----------GSGVGATGG---------------VRKVFTNTRERWR 177
            .|..|..:.|....||..          ...|||..|               .|::..|.|||.|
Zfish    66 SSAEGVSSASNFRKSSKSPVKVRELCRLKGAVGADEGRQRAPSSKSTNVVQKQRRMAANARERRR 130

  Fly   178 QQNVSGAFAELRKLVPTHPPDKKLSKNEILRSAIKYIKLLTGILEWQQRQAPSHPIRAQMEPNNN 242
            ...::.||.|||.::|....||||||.|.|:.|..||..|:.:|     |.|.    |:.:|.|.
Zfish   131 MHGLNHAFDELRSVIPAFDNDKKLSKYETLQMAQIYINALSDLL-----QGPG----AKADPPNC 186

  Fly   243 DNRMANGHAADGENLENPDVPPVRHIKCERTDGQMHRNGIGHGHANGNAGNDLLMIAPGAVVKSE 307
            |...||....|.....:|.|       |.|..|..:......|..|.....||.  :|....||.
Zfish   187 DLLHANVLETDRSPRGSPGV-------CRRGTGVGYPYQYEDGTFNSFMEQDLQ--SPSGTSKSG 242

  Fly   308 LLLESTLPLGHPLNGPPLPLTTAPLAMAETQRISGTVSGVKSASGRSSKR-RLKPEGGATDLSLG 371
            .......|                    .:.|..|..|.....|...... .|:.|...::|.|.
Zfish   243 SEASKDSP--------------------RSNRSDGEFSPHSHFSDSDETHLELQSEDELSELKLA 287

  Fly   372 KRR 374
            |||
Zfish   288 KRR 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLH3B	NP_525055.1	bHLH_TS_dHLH3B_like	166..225	CDD:381551	25/58 (43%)
atoh1a	NP_571166.2	bHLH_TS_ATOH1	114..177	CDD:381556	26/67 (39%)