Protein Alignment HLH3B and Ascl5

DIOPT Version :10

• Sequence 1: NP_525055.1
• Gene: HLH3B / 31249
• FlyBaseID: FBgn0011276
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001257538.1
• Gene: Ascl5 / 226439
• MGIID: 2685043
• Length: 188
• Species: Mus musculus
• Alignment Length: 145
• Identity: 40/145 - (27%)
• Similarity: 55/145 - (37%)
• Gaps: 44/145 - (30%)

  Fly   171 NTRERWRQQNVSGAFAELRKLVPTHPPDKKLSKNEILRSAIKYIKLLTGILEWQQRQAPSHPIRA 235
            |.|||.|.:.|:..:|.||..:|....:|:|||.|.||:||:|||.|..:|......||
Mouse    86 NERERQRVKCVNEGYARLRGHLPGALTEKRLSKVETLRAAIRYIKYLQELLSATPDGAP------ 144

  Fly   236 QMEPNNNDNRMANGHAADGENLENPDVPPVRHIKCERTDGQMHRNGIGHGHANGNAGNDLLMIAP 300
              .|..:                    ||..|.                ||:|....:.|:..:.
Mouse   145 --PPATS--------------------PPPAHT----------------GHSNVPQPSSLVAESS 171

  Fly   301 GAVVKSELLLESTLP 315
            |:...|...|||..|
Mouse   172 GSPFSSSPFLESEEP 186

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLH3B	NP_525055.1	bHLH_TS_dHLH3B_like	166..225	CDD:381551	24/53 (45%)
Ascl5	NP_001257538.1	bHLH_TS_ASCL5	76..136	CDD:381590	23/49 (47%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00981	80..93		4/6 (67%)
		Helix-loop-helix motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00981	94..132		17/37 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	139..188		16/92 (17%)