Protein Alignment HLH3B and Mesp2

DIOPT Version :10

• Sequence 1: NP_525055.1
• Gene: HLH3B / 31249
• FlyBaseID: FBgn0011276
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_032615.2
• Gene: Mesp2 / 17293
• MGIID: 1096325
• Length: 370
• Species: Mus musculus
• Alignment Length: 352
• Identity: 75/352 - (21%)
• Similarity: 105/352 - (29%)
• Gaps: 148/352 - (42%)

  Fly   113 LSSSPRSHSRNGL----------------LTAPASSGSSVGG-----------SGGGGGNGSGGN 150
            ::.||...|..||                .|:||||..|.|.           ..|...:.....
Mouse     1 MAQSPPPQSLQGLDHWVFSQGWGWAQQSDSTSPASSSDSSGSCPCYATRRPSQPAGPARSTRTTQ 65

  Fly   151 ASSGGGSGVGATGGVRKVFTNTRERWRQQNVSGAFAELRKLVP--THPPDKKLSKNEILRSAIKY 213
            |::...:.....||.|: ..:.||:.|.:.::.|..|||:.:|  ..|..:.|:|.|.||.||:|
Mouse    66 ATAPRRTRPAPAGGQRQ-SASEREKLRMRTLARALQELRRFLPPSVAPAGQSLTKIETLRLAIRY 129

  Fly   214 I---KLLTGILEWQQRQ--------APSH----------PIRAQM-------------------- 237
            |   ..|.|:.|...|:        |.||          |.:|||
Mouse   130 IGHLSALLGLSEDSLRRRRRRSADAAFSHRCPQCPDGGSPSQAQMLGPSLGSAMSSGVSWGCPPA 194

  Fly   238 ------EPNNNDNRMAN---------------------GHAADGENLENPDVPPVRHIKCERTDG 275
                  .|.|..||::|                     ..|||......|...|...:..|
Mouse   195 CPGPLISPENLGNRISNVDPWVTPPYCPQIQSPLHQSLERAADSSPWAPPQACPGMQMSPE---- 255

  Fly   276 QMHRNGIGHGHANGNAGN-----DLLMIAPGAVVKSELLLESTLPLGHPLNGPPLPLTTAPLAMA 335
              .||..||...:.....     ..|.::|          |..|.||.||..|
Mouse   256 --PRNKTGHWTQSTEPAELTKVYQSLSVSP----------EPCLSLGSPLLLP------------ 296

  Fly   336 ETQRISGTVSGVKSASGRSSKRRLKPE 362
                             |.|.:||:|:
Mouse   297 -----------------RPSCQRLQPQ 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLH3B	NP_525055.1	bHLH_TS_dHLH3B_like	166..225	CDD:381551	22/63 (35%)
Mesp2	NP_032615.2	bHLH_TS_Mesp	80..144	CDD:381508	22/64 (34%)