Protein Alignment HLH3B and Ascl2

DIOPT Version :9

• Sequence 1: NP_525055.1
• Gene: HLH3B / 31249
• FlyBaseID: FBgn0011276
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_032580.2
• Gene: Ascl2 / 17173
• MGIID: 96920
• Length: 263
• Species: Mus musculus
• Alignment Length: 285
• Identity: 63/285 - (22%)
• Similarity: 90/285 - (31%)
• Gaps: 119/285 - (41%)

  Fly     3 W--LPSSSNGADNADERSTASS------GSSGHSQTNESPR-----------SGHLNGNGSMRDT 48
            |  :|.....:|.....|.:|:      |::.|...:..||           :|....|.|:.|.
Mouse     7 WYGVPGLQEASDACPRESCSSALPEAREGANVHFPPHPVPREHFSCAAPELVAGAQGLNASLMDG 71

  Fly    49 AAGRHPPALLRHATPHLQPKTESISDGDGDAELSDFSLNDTEEDEEDLRDYIVLNGNQADANRSL 113
            .           |.|.|.|.:..::.                                |.|.|..
Mouse    72 G-----------ALPRLMPTSSGVAG--------------------------------ACAARRR 93

  Fly   114 SSSPR----SHSRNGLLTAPASSGSSVGGSGGGGGNGSGGNASSGGGSGVGATGGVRKVFTNTRE 174
            .:||.    |..|....|..:||.::|                            .|:   |.||
Mouse    94 QASPELLRCSRRRRSGATEASSSSAAV----------------------------ARR---NERE 127

  Fly   175 RWRQQNVSGAFAELRKLVPTHPPDKKLSKNEILRSAIKYIKLLTGILEWQQRQAPSHPIRAQMEP 239
            |.|.:.|:..|..||:.||....:|||||.|.||||::||:.|..:|      |....:||
Mouse   128 RNRVKLVNLGFQALRQHVPHGGANKKLSKVETLRSAVEYIRALQRLL------AEHDAVRA---- 182

  Fly   240 NNNDNRMANGHAADGENLENPDVPP 264
                 .:|.|       |..|..||
Mouse   183 -----ALAGG-------LLTPATPP 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLH3B	NP_525055.1	HLH	171..222	CDD:197674	24/50 (48%)
Ascl2	NP_032580.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	104..126		7/52 (13%)
		HLH	134..176	CDD:197674	20/47 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..248		2/2 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900