Protein Alignment HLH3B and OLIG3

DIOPT Version :10

• Sequence 1: NP_525055.1
• Gene: HLH3B / 31249
• FlyBaseID: FBgn0011276
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_786923.1
• Gene: OLIG3 / 167826
• HGNCID: 18003
• Length: 272
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 66/306 - (21%)
• Similarity: 105/306 - (34%)
• Gaps: 108/306 - (35%)

  Fly   102 LNGNQADANRSLSSSP--------------RSHSRNGLLTAPASSGSSVGGSGGGGGNGSGGNAS 152
            :|.:.:..: |.:|||              ..|..:.|.:..::.|..:....|...:.:|..|
Human     1 MNSDSSSVS-SRASSPDMDEMYLRDHHHRHHHHQESRLNSVSSTQGDMMQKMPGESLSRAGAKA- 63

  Fly   153 SGGGSGVGATGGVRKVFT-----------NTRERWRQQNVSGAFAELRKLVP-THPPD-KKLSKN 204
                :|..:...::|..:           |.|||.|..:::.|...||:::| .|.|. :||||.
Human    64 ----AGESSKYKIKKQLSEQDLQQLRLKINGRERKRMHDLNLAMDGLREVMPYAHGPSVRKLSKI 124

  Fly   205 EILRSAIKYIKLLTGILEWQQR-------------------QAPSHPIRAQMEPNNNDNRMANGH 250
            ..|..|..||.:||..||..:|                   .:..||                .|
Human   125 ATLLLARNYILMLTSSLEEMKRLVGEIYGGHHSAFHCGTVGHSAGHP----------------AH 173

  Fly   251 AADGENLENPDVPPVRHIKCERTDGQMHRNGIGHGHANGNAGNDL---LMIAPGAVVKSELLLES 312
            ||:       .|.||..|             :|...::|||.:.|   .:.|.|.:.....||::
Human   174 AAN-------SVHPVHPI-------------LGGALSSGNASSPLSAASLPAIGTIRPPHSLLKA 218

  Fly   313 -----TLPLGHPLN---GPPLPLT---------TAPLAMAETQRIS 341
                 .|.||....   |.|.|.|         .:.|:.|...|:|
Human   219 PSTPPALQLGSGFQHWAGLPCPCTICQMPPPPHLSALSTANMARLS 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLH3B	NP_525055.1	bHLH_TS_dHLH3B_like	166..225	CDD:381551	24/71 (34%)
OLIG3	NP_786923.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		12/75 (16%)
		bHLH_TS_OLIG3	69..149	CDD:381511	25/79 (32%)