Protein Alignment HLH3B and BHLHE23

DIOPT Version :10

• Sequence 1: NP_525055.1
• Gene: HLH3B / 31249
• FlyBaseID: FBgn0011276
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_542173.2
• Gene: BHLHE23 / 128408
• HGNCID: 16093
• Length: 241
• Species: Homo sapiens
• Alignment Length: 204
• Identity: 52/204 - (25%)
• Similarity: 75/204 - (36%)
• Gaps: 43/204 - (21%)

  Fly    65 LQPKTESISDGDGD-AELSDFSLNDTEEDEEDLRDYIVLNGNQADANRSLS-------SSPRSHS 121
            ::|..|..|.|... |||...| .|.         |:.|:...|.|...|:       .:.|.:.
Human     3 IRPPGEPPSPGGAAMAELKSLS-GDA---------YLALSHGYAAAAAGLAYGAAREPEAARGYG 57

  Fly   122 RNG----LLTAPASSGSSVGGSGGGGGNGSGGNA----SSGGGSGVGATGGVR-------KVFTN 171
            ..|    |..|||....:......|..:|...:|    ....|.|..|.|..|       ::..|
Human    58 TPGPGGDLPAAPAPRAPAQAAESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSLRLSIN 122

  Fly   172 TRERWRQQNVSGAFAELRKLVP-THPPD-KKLSKNEILRSAIKYIKLLTGILEWQQR-------- 226
            .|||.|..:::.|...||.::| .|.|. :||||...|..|..||.:....|:..:|
Human   123 ARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQG 187

  Fly   227 QAPSHPIRA 235
            |..:.|:.|
Human   188 QGLAAPVNA 196

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLH3B	NP_525055.1	bHLH_TS_dHLH3B_like	166..225	CDD:381551	21/67 (31%)
BHLHE23	NP_542173.2	bHLH_SF	111..191	CDD:469605	22/79 (28%)