Protein Alignment HLH3B and Neurog2

DIOPT Version :10

• Sequence 1: NP_525055.1
• Gene: HLH3B / 31249
• FlyBaseID: FBgn0011276
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_033848.1
• Gene: Neurog2 / 11924
• MGIID: 109619
• Length: 263
• Species: Mus musculus
• Alignment Length: 306
• Identity: 72/306 - (23%)
• Similarity: 109/306 - (35%)
• Gaps: 108/306 - (35%)

  Fly    84 FSLNDTEEDEEDLRDYIVLNGNQADANRSLS--SSPRSHSRNGLLTAPASSGSSVGGSGGGGGNG 146
            |..::|.|.:|: .:.::|.|:.:.|:.:|:  ||......:..|..|   ||:.|..|...|.|
Mouse     2 FVKSETLELKEE-EEVLMLLGSASPASATLTPMSSSADEEEDEELRRP---GSARGQRGAEAGQG 62

  Fly   147 SGGNASSG-GGSGVGATGGV------------------------------RKVFTNTRERWRQQN 180
            ..|:.:|| ||...|...|:                              |::..|.|||.|..|
Mouse    63 VQGSPASGAGGCRPGRLLGLMHECKRRPSRSRAVSRGAKTAETVQRIKKTRRLKANNRERNRMHN 127

  Fly   181 VSGAFAELRKLVPTHPPDKKLSKNEILRSAIKYIKLLTGILEWQQRQAPSHPIRAQMEPNNNDNR 245
            ::.|...||:::||.|.|.||:|.|.||.|..||..||..|                       |
Mouse   128 LNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETL-----------------------R 169

  Fly   246 MANGHAADGENLENPDVPPVRHIKCERTDGQMHRNGIGHGHANGNAGNDLLMIAPGAVVKSELLL 310
            :|: |.|                              |.|...|....:.::::|||.
Mouse   170 LAD-HCA------------------------------GAGGLQGALFTEAVLLSPGAA------- 196

  Fly   311 ESTLPLGHPLNGPPLP----LTTAPLAMA-ETQRISGTVSGVKSAS 351
                 ||...:.|..|    .|.:|.:.: .|...|.|:|.....|
Mouse   197 -----LGASGDSPSPPSSWSCTNSPASSSNSTSPYSCTLSPASPGS 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLH3B	NP_525055.1	bHLH_TS_dHLH3B_like	166..225	CDD:381551	26/58 (45%)
Neurog2	NP_033848.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..76		18/58 (31%)
		bHLH_TS_NGN2_ATOH4	104..172	CDD:381560	27/90 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..253		11/41 (27%)