Protein Alignment HLH3B and Neurod6

DIOPT Version :10

• Sequence 1: NP_525055.1
• Gene: HLH3B / 31249
• FlyBaseID: FBgn0011276
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_033847.1
• Gene: Neurod6 / 11922
• MGIID: 106593
• Length: 337
• Species: Mus musculus
• Alignment Length: 208
• Identity: 51/208 - (24%)
• Similarity: 72/208 - (34%)
• Gaps: 52/208 - (25%)

  Fly   157 SGVGATGGVRKVFT---------------NTRERWRQQNVSGAFAELRKLVPTHPPDKKLSKNEI 206
            :|:....|:||..|               |.|||.|...::.|...|||:||.:...:||||.|.
Mouse    71 NGLSRRRGLRKKKTTKLRLERVKFRRQEANARERNRMHGLNDALDNLRKVVPCYSKTQKLSKIET 135

  Fly   207 LRSAIKYIKLLTGILEWQQR---------------QAPSHPIRAQMEPNNNDNRMANGHAADGEN 256
            ||.|..||..|:.||...:|               |..::.:...::.|.....|..|..| ..:
Mouse   136 LRLAKNYIWALSEILRIGKRPDLLTFVQNLCKGLSQPTTNLVAGCLQLNARSFLMGQGGEA-AHH 199

  Fly   257 LENP---DVPPVRHIKCERTDGQMHRNGIGHGHANGNAGNDLLMIAPGAVVKSELLLESTLP--- 315
            ..:|   ..||            .|...:.....:|...|...|.........|...|||.|
Mouse   200 TRSPYSTFYPP------------YHSPELATPPGHGTLDNSKSMKPYNYCSAYESFYESTSPECA 252

  Fly   316 ---LGHPLNGPPL 325
               ...||:.||:
Mouse   253 SPQFEGPLSPPPI 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HLH3B	NP_525055.1	bHLH_TS_dHLH3B_like	166..225	CDD:381551	27/73 (37%)
Neurod6	NP_033847.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	28..80		2/8 (25%)
		Nuclear localization signal. /evidence=ECO:0000255	80..86		3/5 (60%)
		bHLH_TS_NeuroD6_ATOH2	82..151	CDD:381565	24/68 (35%)
		Neuro_bHLH	153..272	CDD:463621	22/126 (17%)