DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sgg and SK42

DIOPT Version :9

Sequence 1:	NP_001259193.1	Gene:	sgg / 31248	FlyBaseID:	FBgn0003371	Length:	1168	Species:	Drosophila melanogaster
Sequence 2:	NP_001185256.1	Gene:	SK42 / 842162	AraportID:	AT1G57870	Length:	443	Species:	Arabidopsis thaliana

Alignment Length:	426	Identity:	237/426 - (55%)
Similarity:	300/426 - (70%)	Gaps:	30/426 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   551 GSGENVKTAKLARTQSCVSWTKVVQKFKNILGMKQLIGKLNDLWPEHSVALSIPKEVDRSKEKLE 615
            ||..:.|..|  .|.|.|.|..     :::|.|     |:.|           ..|.|..::...
plant    10 GSSRSAKNTK--NTSSSVDWLS-----RDMLEM-----KIRD-----------KTEADEERDSEP 51

  Fly   616 GAWETTGRD-GSKITTVVATPGQGTDRVQEVSYTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVL 679
            ...:..|.: |..|||.:  ||:.....|.|||....|:|.||||:|||||..:|||:|||||||
plant    52 DIIDGVGAEPGHVITTTL--PGRNGQSRQTVSYIAEHVVGTGSFGMVFQAKCRETGEVVAIKKVL 114

  Fly   680 QDRRFKNRELQIMRKLEHCNIVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTI 744
            ||:|:||||||||:.|:|.|:|.|.:.|||..| .:||:||||||::||||.:.||.|::..|.:
plant   115 QDKRYKNRELQIMQMLDHPNVVCLKHSFYSRTE-NEEVYLNLVLEFVPETVNRTARSYSRMNQLM 178

  Fly   745 PINFIRLYMYQLFRSLAYIHS-LGICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLHGEPNVSYI 808
            |:.:::||.||:.|.|||:|: .|:|||||||||||::|.|..||:|||||||.|:.||||:|||
plant   179 PLIYVKLYTYQICRGLAYLHNCCGLCHRDIKPQNLLVNPHTHQLKICDFGSAKVLVKGEPNISYI 243

  Fly   809 CSRYYRAPELIFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTREQIR 873
            ||||||||||||||..|||.||:||.|||:||||||||:|||:||||||||:||||||||||:|:
plant   244 CSRYYRAPELIFGATEYTTAIDIWSTGCVMAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIK 308

  Fly   874 EMNPNYTEFKFPQIKSHPWQKVFRIRTPTEAINLVSLLLEYTPSARITPLKACAHPFFDELRMEG 938
            .||||||||||||||.|||.|||:.|.|.||::|:....:|:|:.|.|.::||.|||||||| :.
plant   309 CMNPNYTEFKFPQIKPHPWHKVFQKRLPPEAVDLLCRFFQYSPNLRCTAVEACIHPFFDELR-DP 372

  Fly   939 NHTLPNGRDMPPLFNFTEHELS-IQPSLVPQLLPKH 973
            |..|||||.:||||||...||| |.|..|.:|:|:|
plant   373 NARLPNGRPLPPLFNFKPQELSGIPPETVDRLVPEH 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sgg	NP_001259193.1	STKc_GSK3	643..934	CDD:271039	192/291 (66%)
sgg	NP_001259193.1	S_TKc	647..931	CDD:214567	186/284 (65%)
SK42	NP_001185256.1	STKc_GSK3	77..369	CDD:271039	192/292 (66%)
SK42	NP_001185256.1	S_TKc	82..366	CDD:214567	186/284 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	418	1.000	Domainoid score	I124
eggNOG	1	0.900	-	-		E2759_KOG0658
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	462	1.000	Inparanoid score	I363
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D990896at2759
OrthoFinder	1	1.000	-	-		FOG0000635
OrthoInspector	1	1.000	-	-		mtm986
orthoMCL	1	0.900	-	-		OOG6_100482
Panther	1	1.100	-	-	O	PTHR24057
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X378
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.830