DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sgg and SK32

DIOPT Version :9

Sequence 1:	NP_001259193.1	Gene:	sgg / 31248	FlyBaseID:	FBgn0003371	Length:	1168	Species:	Drosophila melanogaster
Sequence 2:	NP_191981.1	Gene:	SK32 / 828023	AraportID:	AT4G00720	Length:	472	Species:	Arabidopsis thaliana

Alignment Length:	460	Identity:	249/460 - (54%)
Similarity:	323/460 - (70%)	Gaps:	32/460 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   549 SDGSGE-NVKTAKLARTQS--CVSWTKVVQKFK------NILGMKQLIGKLN----------DLW 594
            ||..|: .:|.|||.:...  ||...:|.|...      ::|..:.:.|..|          |..
plant    19 SDPGGDYALKRAKLDQENDNLCVDPMQVDQNSSCFEMKADVLSQESVAGTSNVPAVSEKPVDDQL 83

  Fly   595 PEHSVALSIPKEVDRSKEKLEGAWETTGRDGSKITT--VVATPGQGTD--RVQEVSYTDTKVIGN 655
            |:..:.:.|..|.:.::|..:  .|||..:||...|  |:.|...|.|  ..|.:||...:|:|.
plant    84 PDVMIEMKIRDERNANREDKD--METTVVNGSGTETGQVITTTVGGRDGKPKQTISYMAQRVVGT 146

  Fly   656 GSFGVVFQAKLCDTGELVAIKKVLQDRRFKNRELQIMRKLEHCNIVKLLYFFYSSGEKRDEVFLN 720
            ||||||||||..:|||.|||||||||:|:|||||||||..:|.|:|:|.:.|:|:.:| ||::||
plant   147 GSFGVVFQAKCLETGEQVAIKKVLQDKRYKNRELQIMRLQDHPNVVRLRHSFFSTTDK-DELYLN 210

  Fly   721 LVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFRSLAYIHS-LGICHRDIKPQNLLLDPET 784
            |||||:|||||:.::.|.|..|.:||.|::||.||:.|:|.|:|. :|:|||||||||||::|:|
plant   211 LVLEYVPETVYRASKHYTKMNQHMPIIFVQLYTYQICRALNYLHRVVGVCHRDIKPQNLLVNPQT 275

  Fly   785 AVLKLCDFGSAKQLLHGEPNVSYICSRYYRAPELIFGAINYTTKIDVWSAGCVLAELLLGQPIFP 849
            ..||:|||||||.|:.||||:|||||||||||||||||..||..||:||.|||:||||||||:||
plant   276 HQLKICDFGSAKMLVPGEPNISYICSRYYRAPELIFGATEYTNAIDMWSGGCVMAELLLGQPLFP 340

  Fly   850 GDSGVDQLVEVIKVLGTPTREQIREMNPNYTEFKFPQIKSHPWQKVFRIRTPTEAINLVSLLLEY 914
            |:||:|||||:||:|||||||:||.||||||||||||||:|||.|:|..|.|.||::|||.||:|
plant   341 GESGIDQLVEIIKILGTPTREEIRCMNPNYTEFKFPQIKAHPWHKIFHKRMPPEAVDLVSRLLQY 405

  Fly   915 TPSARITPLKACAHPFFDELRMEGNHTLPNGRDMPPLFNFTEHELS-IQPSLVPQLLPKHLQNAS 978
            :|:.|.|.|:||||||||:|| :.|.:|||||.:|||||||..||: ....|..:|:|.|.|
plant   406 SPNLRCTALEACAHPFFDDLR-DPNVSLPNGRALPPLFNFTAQELAGASTELRQRLIPAHCQ--- 466

  Fly   979 GPGGN 983
            |.|.:
plant   467 GTGSS 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sgg	NP_001259193.1	STKc_GSK3	643..934	CDD:271039	196/291 (67%)
sgg	NP_001259193.1	S_TKc	647..931	CDD:214567	191/284 (67%)
SK32	NP_191981.1	STKc_GSK3	133..425	CDD:271039	196/292 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	418	1.000	Domainoid score	I124
eggNOG	1	0.900	-	-		E2759_KOG0658
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	462	1.000	Inparanoid score	I363
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D990896at2759
OrthoFinder	1	1.000	-	-		FOG0000635
OrthoInspector	1	1.000	-	-		mtm986
orthoMCL	1	0.900	-	-		OOG6_100482
Panther	1	1.100	-	-	O	PTHR24057
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X378
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.830