DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sgg and ATSK12

DIOPT Version :9

Sequence 1:	NP_001259193.1	Gene:	sgg / 31248	FlyBaseID:	FBgn0003371	Length:	1168	Species:	Drosophila melanogaster
Sequence 2:	NP_187235.1	Gene:	ATSK12 / 819753	AraportID:	AT3G05840	Length:	409	Species:	Arabidopsis thaliana

Alignment Length:	400	Identity:	236/400 - (59%)
Similarity:	299/400 - (74%)	Gaps:	21/400 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   583 MKQLIGKLNDLWPEHSVALSIPKEVDRSKEKLEGAWETTGRDGSK-------ITTVVATPGQGTD 640
            :::..|.:.|       |..:|:|:...|.:.:...|.|..:|:.       :||:....||..
plant    12 VRESTGNVTD-------ADRLPEEMKDMKIQDDKEMEATIVNGNVTETGHIIVTTIGGRNGQPK- 68

  Fly   641 RVQEVSYTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRRFKNRELQIMRKLEHCNIVKLLY 705
              |.:||...:|:|:||||||||||..:|||.|||||||||||:||||||.||.|:|.|:|.|.:
plant    69 --QTISYMAERVVGHGSFGVVFQAKCLETGETVAIKKVLQDRRYKNRELQTMRLLDHPNVVSLKH 131

  Fly   706 FFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYMYQLFRSLAYIH-SLGIC 769
            .|:|:.|| ||::|||||||:||||::|.:.|.|..|.:|:.:::||.||:||||:||| .:|:|
plant   132 CFFSTTEK-DELYLNLVLEYVPETVHRVIKHYNKLNQRMPLVYVKLYTYQIFRSLSYIHRCIGVC 195

  Fly   770 HRDIKPQNLLLDPETAVLKLCDFGSAKQLLHGEPNVSYICSRYYRAPELIFGAINYTTKIDVWSA 834
            ||||||||||::|.|..:|||||||||.|:.||||:|||||||||||||||||..|||.||||||
plant   196 HRDIKPQNLLVNPHTHQVKLCDFGSAKVLVKGEPNISYICSRYYRAPELIFGATEYTTAIDVWSA 260

  Fly   835 GCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTREQIREMNPNYTEFKFPQIKSHPWQKVFRIR 899
            ||||||||||||:|||:||||||||:||||||||||:|:.||||||||||||||:|||.|:|..|
plant   261 GCVLAELLLGQPLFPGESGVDQLVEIIKVLGTPTREEIKCMNPNYTEFKFPQIKAHPWHKIFHKR 325

  Fly   900 TPTEAINLVSLLLEYTPSARITPLKACAHPFFDELRMEGNHTLPNGRDMPPLFNFTEHELSIQP- 963
            .|.||::|||.||:|:|:.|...|.:..|||||||| :.|..|||||.:||||||..|||...|
plant   326 MPPEAVDLVSRLLQYSPNLRCAALDSLVHPFFDELR-DPNARLPNGRFLPPLFNFKPHELKGVPV 389

  Fly   964 SLVPQLLPKH 973
            .:|.:|:|:|
plant   390 EMVAKLVPEH 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sgg	NP_001259193.1	STKc_GSK3	643..934	CDD:271039	200/291 (69%)
sgg	NP_001259193.1	S_TKc	647..931	CDD:214567	195/284 (69%)
ATSK12	NP_187235.1	STKc_GSK3	68..360	CDD:271039	200/295 (68%)
ATSK12	NP_187235.1	S_TKc	73..357	CDD:214567	195/284 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	418	1.000	Domainoid score	I124
eggNOG	1	0.900	-	-		E2759_KOG0658
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	462	1.000	Inparanoid score	I363
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D990896at2759
OrthoFinder	1	1.000	-	-		FOG0000635
OrthoInspector	1	1.000	-	-		mtm986
orthoMCL	1	0.900	-	-		OOG6_100482
Panther	1	1.100	-	-	O	PTHR24057
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X378
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.830