DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sgg and gsk31

DIOPT Version :9

Sequence 1:	NP_001259193.1	Gene:	sgg / 31248	FlyBaseID:	FBgn0003371	Length:	1168	Species:	Drosophila melanogaster
Sequence 2:	NP_595564.1	Gene:	gsk31 / 2541233	PomBaseID:	SPBC8D2.01	Length:	381	Species:	Schizosaccharomyces pombe

Alignment Length:	363	Identity:	193/363 - (53%)
Similarity:	252/363 - (69%)	Gaps:	19/363 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   624 DGSKITTVVATPGQGTDRVQEVSYTDTKVIGNGSFGVVFQAKLCDTGELVAIKKVLQDRRFKNRE 688
            |.|.:.|.|.|.|. |...:.:||...:|:|:||||||.||||..|...:|:|:||||:|:||||
pombe     3 DDSHLETKVVTDGT-TGEKKTISYEPCRVLGSGSFGVVIQAKLVGTPGFIAVKRVLQDKRYKNRE 66

  Fly   689 LQIMRKLEHCNIVKLLYFFYSSGEKRDEVFLNLVLEYIPETVYKVARQYAKTKQTIPINFIRLYM 753
            |||||.:.|.||:||:.||::....:||..|.|:|||:||||:...|.|.:.:::||...|:||.
pombe    67 LQIMRAISHPNIIKLIAFFHTHNPSKDETHLCLLLEYMPETVFDDMRWYTRRRKSIPNLSIKLYA 131

  Fly   754 YQLFRSLAYIHSLGICHRDIKPQNLLLDPETAVLKLCDFGSAKQLLHGEPNVSYICSRYYRAPEL 818
            :||||:|||:||.|:|||||||||||:|.:|.:||||||||||.|:..|||||||||||||||||
pombe   132 FQLFRALAYLHSTGVCHRDIKPQNLLVDYKTGILKLCDFGSAKVLVPSEPNVSYICSRYYRAPEL 196

  Fly   819 IFGAINYTTKIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEVIKVLGTPTREQIREMNPNYTEFK 883
            :|||.:||||||||||.||:|||.:|:|:|||||.|:||||:|:|||||:..:|..|||||....
pombe   197 VFGATHYTTKIDVWSAACVIAELFIGRPLFPGDSSVEQLVEIIRVLGTPSYHEISVMNPNYVNHS 261

  Fly   884 FPQIKSHPWQKVFRIRTPTEAINLVSLLLEYTPSARITPLKACAHPFFDELRMEGNHTLPN---- 944
            .|.::.|..:.|........|::|:..:|.|.||.||:.::...||||||||.      ||
pombe   262 LPNVRPHTLESVMPHNCTKNAMDLLHKMLTYVPSKRISAIEVLTHPFFDELRD------PNCMYH 320

  Fly   945 --------GRDMPPLFNFTEHELSIQPSLVPQLLPKHL 974
                    .|.:||||||...||||:|:|...:||.|:
pombe   321 CSRDEGTIERHLPPLFNFNLAELSIRPNLNKAILPPHV 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sgg	NP_001259193.1	STKc_GSK3	643..934	CDD:271039	165/290 (57%)
sgg	NP_001259193.1	S_TKc	647..931	CDD:214567	161/283 (57%)
gsk31	NP_595564.1	STKc_GSK3	20..312	CDD:271039	165/291 (57%)
gsk31	NP_595564.1	S_TKc	25..309	CDD:214567	161/283 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0658
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	435	1.000	Inparanoid score	I319
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000635
OrthoInspector	1	1.000	-	-		mtm9293
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24057
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X378
TreeFam	1	0.960	-	-
	8	7.920