DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pi4KIIIalpha and AT1G51040

DIOPT Version :9

Sequence 1:	NP_001259191.1	Gene:	Pi4KIIIalpha / 31247	FlyBaseID:	FBgn0267350	Length:	2154	Species:	Drosophila melanogaster
Sequence 2:	NP_175516.1	Gene:	AT1G51040 / 841525	AraportID:	AT1G51040	Length:	525	Species:	Arabidopsis thaliana

Alignment Length:	599	Identity:	213/599 - (35%)
Similarity:	310/599 - (51%)	Gaps:	93/599 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly  1567 NSLPDLIVPGEEQITEWRNRPYKSTVWRDYARLAWCYNPALAVFLPQRIKNAEIIDEEVSRLVCS 1631
            |.|.|:|....:|..:               :|.|         :.|:...::::..|..|...|
plant     5 NELCDIIEQNPKQFLD---------------KLPW---------ICQQCPQSKLLRAESPRFSQS 45

  Fly  1632 DPIAVCHIPEALKYLCTTKNLLQESPDLVYILSWSPVTPIQALAYFSRQYPSHPLTAQYAVKTLS 1696
            ...|:..:...|..:..|.:   |:...| :|.:....|    ..|.|.:..:.|    :::::|
plant    46 HLNAILAVTRILSKIVDTTD---ENAKFV-VLDFLQTVP----KSFHRSFWPYSL----SLESIS 98

  Fly  1697 SYPAESVLPYIPQLVQALRHDTMGYVVEFIKNISRRSQIVAHQLIWNMQ---TNMYMDEDQQHKD 1758
            ::.. |.|.|:..|.|.:   ..||::    ..::||.|.||.|||::|   ....:.:....|:
plant    99 AFYC-SFLGYVSCLSQLM---VEGYLL----RAAQRSDIFAHTLIWHLQGESVEEIVKDGAFDKN 155

  Fly  1759 PNLYEALDQLSQSIIASFSGAAKRFYEREFDFFGKITAVSGEIRSFAK-----GIERKNACLAAL 1818
            .:..|.|..:.|.|:..|:..|..|:.||||||.|:|::||.:....|     ||.|:      |
plant   156 ASFQEILSDVRQHIVDGFTPKALNFFSREFDFFEKVTSISGALLPLPKEERVAGIRRE------L 214

  Fly  1819 SRIKVQG-GCYLPSNPEAMVLDIDYSSGTPMQSAAKAPYLARFRVYRCGITELETRAMEVSNNPN 1882
            .:||:|| ..|||:.|..:|..|...||.|:|||||.|.:..|.|            :::..:.|
plant   215 EKIKMQGEDLYLPTAPNKLVRVIQVDSGIPLQSAAKVPIMITFNV------------VDLDGDHN 267

  Fly  1883 SQEDAKMTLGVESWQAAIFKVGDDVRQDMLALQVITIFKNIFQQVGLDLFLFPYRVVATAPGCGV 1947
               |.|.       ||.|||||||.|||:||||||::..:|||.|||:|:||||.|:.|.
plant   268 ---DVKP-------QACIFKVGDDCRQDVLALQVISLLGDIFQAVGLNLYLFPYGVLPTV----- 317

  Fly  1948 IECVPNAKSRDQLGRQTDSGLSEYFQHQYGDESSKEFQAARANFVKSMAAYSLIGYLLQIKDRHN 2012
               |||.:||.|:|..||.||.|.||..||...|..|:.|||||:.|.|.|::...|||.|||||
plant   318 ---VPNTRSRSQMGETTDGGLYEIFQQNYGLVGSTTFETARANFLISSAGYAVASLLLQPKDRHN 379

  Fly  2013 GNIMIDKDGHIIHIDFGFMFESSPGGNIGFE-PDMKLTDEMVMIM--GGKMDSPAFKWFCELCVQ 2074
            ||::.|..|.::||||||:.|:|||||:.|| ...||:.||..::  .|.|.|..:..|..|||:
plant   380 GNLLFDDVGRLVHIDFGFILETSPGGNMRFENAHFKLSHEMTQLLDPSGVMKSKTWHQFVSLCVK 444

  Fly  2075 AFLAVRPYQDAIVSLVSLMLDTGLPCF-RGQTINLLKQRFVATKNNKEAAAHMLAVIRNSYQNFR 2138
            .:||.|.|.|.|:|.|.:||::||||| ||..|..|::||....:.:|||..|:.|..::|..:.
plant   445 GYLAARRYMDEIISTVQMMLESGLPCFSRGDPIGNLRKRFHPEMSEREAALFMINVCTDAYNKWT 509

  Fly  2139 TRTYDMIQYYQNQI 2152
            |..||:|||.|..:
plant   510 TAGYDLIQYLQQGV 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pi4KIIIalpha	NP_001259191.1	PI4Ka	1600..1775	CDD:238443	37/177 (21%)
Pi4KIIIalpha	NP_001259191.1	PI4Kc_III_alpha	1836..2153	CDD:270711	144/321 (45%)
AT1G51040	NP_175516.1	PI3Ka	<116..172	CDD:294194	16/59 (27%)
AT1G51040	NP_175516.1	PI4Kc_III_alpha	233..524	CDD:270711	144/321 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	456	1.000	Inparanoid score	I377
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1147978at2759
OrthoFinder	1	1.000	-	-		FOG0002854
OrthoInspector	1	1.000	-	-		otm3337
orthoMCL	1	0.900	-	-		OOG6_101741
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.770