DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pi4KIIIalpha and PI-4KBETA1

DIOPT Version :9

Sequence 1:	NP_001259191.1	Gene:	Pi4KIIIalpha / 31247	FlyBaseID:	FBgn0267350	Length:	2154	Species:	Drosophila melanogaster
Sequence 2:	NP_201212.1	Gene:	PI-4KBETA1 / 836528	AraportID:	AT5G64070	Length:	1121	Species:	Arabidopsis thaliana

Alignment Length:	264	Identity:	113/264 - (42%)
Similarity:	170/264 - (64%)	Gaps:	15/264 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly  1896 W--QAAIFKVGDDVRQDMLALQVITIFKNIFQQVGLDLFLFPYRVVATAPGCGVIECVPNAKSRD 1958
            |  ::.|.|.|||.||:.||:|:|:.|.:|||:.||.|:|.||.|:.|:....:||.:|:..|..
plant   856 WDLRSIIVKSGDDCRQEHLAVQLISHFYDIFQEAGLPLWLRPYEVLVTSSYTALIETIPDTASIH 920

  Fly  1959 QLGRQ--TDSGLSEYFQHQYGDESSKEFQAARANFVKSMAAYSLIGYLLQIKDRHNGNIMIDKDG 2021
            .:..:  ..:.|.::|..:| .|:|..|:.|:.|||:|||.|||:.||||:|||||||:::|::|
plant   921 SIKSRYPNITSLRDFFVAKY-KENSPSFKLAQRNFVESMAGYSLVCYLLQVKDRHNGNLLLDEEG 984

  Fly  2022 HIIHIDFGFMFESSPGGNIGFE-PDMKLTDEMVMIMGGKMD---SPAFKWFCELCVQAFLAVRPY 2082
            ||||||||||..:|||| :.|| ...|||.|::.:|....|   |..|.:|..||:|.||..|.:
plant   985 HIIHIDFGFMLSNSPGG-VNFESAPFKLTRELLEVMDSDADGVPSEFFDYFKVLCIQGFLTCRKH 1048

  Fly  2083 QDAIVSLVSLMLDTGLPCFRG--QTINLLKQRFVATKNNKEAAAHMLAVIRNSYQNFRTRTYDMI 2145
            .:.|:.||.::.|:|.|||:|  :||..|::||..:...::..:.:|::|.:|...:|||.||
plant  1049 AERIILLVEMLQDSGFPCFKGGPRTIQNLRKRFHLSLTEEQCVSLVLSLISSSLDAWRTRQYD-- 1111

  Fly  2146 QYYQ 2149
             |||
plant  1112 -YYQ 1114

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pi4KIIIalpha	NP_001259191.1	PI4Ka	1600..1775	CDD:238443
Pi4KIIIalpha	NP_001259191.1	PI4Kc_III_alpha	1836..2153	CDD:270711	113/264 (43%)
PI-4KBETA1	NP_201212.1	TFIIF_alpha	<230..540	CDD:253391
PI-4KBETA1	NP_201212.1	PI4Kc_III_beta	831..1121	CDD:270712	113/264 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1147978at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820