Protein Alignment Pi4KIIIalpha and pik3c3

DIOPT Version :9

• Sequence 1: NP_001259191.1
• Gene: Pi4KIIIalpha / 31247
• FlyBaseID: FBgn0267350
• Length: 2154
• Species: Drosophila melanogaster
• Sequence 2: XP_031750800.1
• Gene: pik3c3 / 100485933
• XenbaseID: XB-GENE-6085226
• Length: 887
• Species: Xenopus tropicalis
• Alignment Length: 603
• Identity: 148/603 - (24%)
• Similarity: 243/603 - (40%)
• Gaps: 145/603 - (24%)

  Fly  1644 KYL-CTTKNLLQESPDLVYIL-SWSPVTPIQALAYFSRQYPSHPLTAQYAVKTLSSYPAESVLPY 1706
            |:| |...:|.||:...:.:| .|.|:....:|...|..: ::|...:|||..|.....|.:|.|
 Frog   332 KFLKCVNWDLPQEAKQALELLGKWKPMDVEDSLELLSSHF-TNPTVRRYAVARLQQADDEDLLMY 395

  Fly  1707 IPQLVQALRH---------------DTMGYVVE---------------FIKN------------- 1728
            :.||||||::               |:.|.::|               .|.|
 Frog   396 LLQLVQALKYENFEDIKSGLEPTKKDSQGPMLESMTTSGINPESDSSQVISNPLPSAVSSPAPSS 460

  Fly  1729 -------------------ISR--RSQIVAHQLIWNMQTNMYM-----DEDQQHKDPNLYE---- 1763
                               |||  ::..:|:.|.|      |:     |:|.|.:||..:|
 Frog   461 KTKDGLDAENLEQDLCTFLISRACKNSTLANYLYW------YVIVECEDQDTQLRDPKTHEMYLN 519

  Fly  1764 ALDQLSQS---------IIASFSGAAKRFYEREFDFFGKITAVSGEIRSFAKGIERKNACLAALS 1819
            .:.:.||:         ::.|.....:.|.:|.......:...||..:   |..||..|.|....
 Frog   520 VMRRFSQALLKGDKSVRVMRSLLATQQTFVDRLVHLMKAVQRESGNRK---KKNERLQALLGDNE 581

  Fly  1820 RIKVQ--GGCYLPSNPEAMVLDIDYSSGTPMQSAAKAPYLARFRVYRCGITELETRAMEVSNNPN 1882
            ::.:.  ....||..|:..:..|.....|..:||..
 Frog   582 KMNLSEFEPIPLPLEPQVKIRGIIPEKATLFKSALM----------------------------- 617

  Fly  1883 SQEDAKMTLGVESW--QAAIFKVGDDVRQDMLALQVITIFKNIFQQVGLDLFLFPYRVVATAPGC 1945
               .||:....|..  ...|||.|||:|||.|.||:|::...:.::..|||.|.||:|:||:...
 Frog   618 ---PAKLYFKTEDGGRYPVIFKNGDDLRQDQLILQIISLMDKLLRKENLDLKLTPYKVLATSTKH 679

  Fly  1946 GVIECVPNAKSRDQLGRQTDSGLSEYFQHQYGDESSKEFQAARA--NFVKSMAAYSLIGYLLQIK 2008
            |.::.:.:....:.|.  |:..:..:|:.....|......:|..  .:|||.|.|.:|.|:|.:.
 Frog   680 GFMQFIQSVPVAEVLA--TEGSIQNFFRKYAPSEKGPYGISAEVMDTYVKSCAGYCVITYILGVG 742

  Fly  2009 DRHNGNIMIDKDGHIIHIDFGFMFESSPGGNIGFEPDMKLTDEMVMIMGGKMDSPAFKWFCELCV 2073
            |||..|:::.|.|.:.|||||::....|.   ...|.|||..|||..||| ..|..::.|.:.|.
 Frog   743 DRHLDNLLLTKTGKLFHIDFGYILGRDPK---PLPPPMKLNKEMVEGMGG-TQSEQYQAFRKQCY 803

  Fly  2074 QAFLAVRPYQDAIVSLVSLMLDTGLPCFR---GQTINLLKQRFVATKNNKEAAAHMLAVIRNSYQ 2135
            .|||.:|.|.:.|::|.|||:|..:|...   .:|:..::.:|....:::||..:|..:|.:|..
 Frog   804 TAFLHLRRYSNLILNLFSLMVDANIPDIALEPDKTVKKVQDKFRLDLSDEEAVHYMQTLIDDSVN 868

  Fly  2136 NFRTRTYDMI----QYYQ 2149
            .......:.|    ||::
 Frog   869 ALFAAVVEQIHKFAQYWR 886

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pi4KIIIalpha	NP_001259191.1	PI4Ka	1600..1775	CDD:238443	45/214 (21%)
		PI4Kc_III_alpha	1836..2153	CDD:270711	90/325 (28%)
pik3c3	XP_031750800.1	C2_PI3K_class_III	26..186	CDD:176042
		PI3Ka_III	283..503	CDD:238442	37/177 (21%)
		PI3Kc_III	539..883	CDD:270628	101/384 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000