Protein Alignment Pi4KIIIalpha and pi4kb

DIOPT Version :9

• Sequence 1: NP_001259191.1
• Gene: Pi4KIIIalpha / 31247
• FlyBaseID: FBgn0267350
• Length: 2154
• Species: Drosophila melanogaster
• Sequence 2: NP_001096204.1
• Gene: pi4kb / 100124755
• XenbaseID: XB-GENE-997612
• Length: 806
• Species: Xenopus tropicalis
• Alignment Length: 716
• Identity: 174/716 - (24%)
• Similarity: 284/716 - (39%)
• Gaps: 199/716 - (27%)

  Fly  1630 CSDPIAVCHIPEALKYLC----------TTKNLLQESPDLVYILSWSPVTPIQALAYFSRQYPS- 1683
            |..|::...|.|..:.|.          ..||...:...|:.:..........|::|.   |.|
 Frog    96 CGPPVSASRITEEEESLIDINSVKSARRRQKNNSAKQSWLLRLFECKLFDVSMAISYL---YNSK 157

  Fly  1684 HPLTAQYAVKTLSSYPAESVLPYIPQLVQALRH---DTMGYVVEFIKNISRRSQIVAHQLIWNM- 1744
            .|....|....|..:..|.|..|:|||:....|   |....:..::.:..|:|...:.|..|.:
 Frog   158 EPGVQAYIGNRLFCFRYEDVDFYLPQLLNMYIHMDEDVGDAIKPYVVHRCRQSINFSLQCAWLLG 222

  Fly  1745 --QTNMYMDEDQQHKDPNLYEAL--DQLSQS---------IIASFSG--AAKRFYER-------- 1786
              .::|::...:..:...|.:.:  |:|..:         .:|..:|  .:||.::|
 Frog   223 AYSSDMHISTQRHSRGTKLRKLILSDELKPAHKKREIPPLSLAPDTGLSPSKRTHQRSKSDATVS 287

  Fly  1787 ---------------------------EFDFFGKITAVSGEIRSFAKGIERKNACLAALSRI--K 1822
                                       |.:|...:.|:...:.:.....::....::.||.:  |
 Frog   288 ISLSSNLKRTSSNPKVENDDEPVRLAPEREFIKSLMAIGKRLATLPTKEQKTQRLISELSLLNHK 352

  Fly  1823 VQGGCYLP-SNPEAMVLDIDYSSGTPMQSAAKAPYLA----------------------RFRVYR 1864
            :....:|| :..:..|:.:.::....:.|..|||||.                      |.|..|
 Frog   353 LPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFETSLVPVRIPENRIRSTR 417

  Fly  1865 -------CGITELETRAMEVSNNPN---------------------------------------- 1882
                   ||||. |.||...:..||
 Frog   418 SVENLPECGITH-EQRASSFTTVPNYDNDDEAWSVDDIGELQVELPELHTNSCDNISQFSVDSIT 481

  Fly  1883 SQE----------DAKMTLG----------------------VESWQ------------------ 1897
            |||          |.:..|.                      .|.||
 Frog   482 SQESKDPVFIAAGDIRRRLSEQLAHTPTTFRRDPEDPSAVALKEPWQEKVRRIREGSPYGHFPNW 546

  Fly  1898 ---AAIFKVGDDVRQDMLALQVITIFKNIFQQVGLDLFLFPYRVVATAPGCGVIECVPNAKSRDQ 1959
               :.|.|.|||:||::||.||:...::|::...:.|::.||:::..:...|:||.|.||.|..|
 Frog   547 RLLSVIVKCGDDLRQELLAYQVLKQLQSIWESERVPLWIRPYKILVISADSGMIEPVVNAVSIHQ 611

  Fly  1960 LGRQTDSGLSEYFQHQYGDESSKEFQAARANFVKSMAAYSLIGYLLQIKDRHNGNIMIDKDGHII 2024
            :.:|:...|.:||..::|..:::.|..|:.|||:|.|.|.|:.||||:||||||||::|.:||||
 Frog   612 VKKQSQLSLLDYFLQEHGSCTTEAFLTAQRNFVQSCAGYCLVCYLLQVKDRHNGNILLDAEGHII 676

  Fly  2025 HIDFGFMFESSPGGNIGFEPD-MKLTDEMVMIMGGKMDSPAFKWFCELCVQAFLAVRPYQDAIVS 2088
            ||||||:..||| .|:|||.. .|||.|.|.:||| ::...|.::..|.:|..:|.|.:.|.:|.
 Frog   677 HIDFGFILSSSP-RNLGFETSAFKLTSEFVDVMGG-LNGDMFNYYKMLMLQGLIAARKHMDRVVQ 739

  Fly  2089 LVSLMLD-TGLPCFRG-QTINLLKQRFVATKNNKEAAAHMLAVIRNSYQNFRTRTYDMIQYYQNQ 2151
            :|.:|.. :.||||.| .||..||:||......::....:..::..|.::..|:.||..||..|.
 Frog   740 IVEIMQQGSQLPCFHGSSTIRNLKERFHMNMTEEQLQVLVEQMVDGSMRSITTKLYDGFQYLTNG 804

  Fly  2152 I 2152
            |
 Frog   805 I 805

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pi4KIIIalpha	NP_001259191.1	PI4Ka	1600..1775	CDD:238443	31/172 (18%)
		PI4Kc_III_alpha	1836..2153	CDD:270711	130/442 (29%)
pi4kb	NP_001096204.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	69..104		2/7 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	253..310		5/56 (9%)
		PI4Kc_III_beta	519..806	CDD:270712	106/289 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1147978at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920