Protein Alignment brv3 and Pkd2l2

DIOPT Version :9

• Sequence 1: NP_001284831.1
• Gene: brv3 / 31246
• FlyBaseID: FBgn0040333
• Length: 750
• Species: Drosophila melanogaster
• Sequence 2: XP_017173433.1
• Gene: Pkd2l2 / 53871
• MGIID: 1858231
• Length: 623
• Species: Mus musculus
• Alignment Length: 685
• Identity: 145/685 - (21%)
• Similarity: 256/685 - (37%)
• Gaps: 173/685 - (25%)

  Fly   110 TSRY-RNYKLNDQYKMIAHDLFIYGPYFLCLMCLVLVTRDQTLYHNTRIITDLFM---YNHTDYT 170
            ||:: .:|:...:......:|.:|..:.:.|..|.....:..:|:..::::.||:   ....:.:
Mouse    14 TSKHDLHYRREAEVNTTLEELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFVDTSLPDDERS 78

  Fly   171 GLQEVYFLNQLFDFIESTLV--LAFNSNSTESGSPGWAHAEQ-------------SVLLGVMRLR 220
            ..:.:..:.:.:.|:|..|:  |.::|         |...:|             :||||:.|:|
Mouse    79 SFRSIRSITEFWKFMEGPLIDGLYWDS---------WYGNKQLYSVKNSSRIYYENVLLGIPRVR 134

  Fly   221 QLRVSNPQVGLGP---PKFSDTYYM----------------PDW-QLPYRKLHYSDKYWRIYEPW 265
            ||||.|....:.|   ...||.|..                |:| ..|..:.          .||
Mouse   135 QLRVRNNTCKVYPAFQSLVSDCYSKYTVENEDFSDFGLKRNPEWTHTPSSRT----------APW 189

  Fly   266 IPIKMGFEFLDALLMNFDHVGSLNSYPELAGYVSLLARSAANS-MKVIDYLSENHWLTLNTSAVF 329
                              |.|.:..|.: .||:..|::|.:.: .|.:| |..|:|::..|.|||
Mouse   190 ------------------HWGFVGVYRD-GGYIVTLSKSKSETKAKFVD-LRLNNWISRGTRAVF 234

  Fly   330 IDFTLYNVDVNLFSICTLRVEKTPFGGIVPDVQVDSAKLLENVDQMPY-TGLLALLIYVLVFIQF 393
            |||:|||.:||||.|..|..|....||::...|..|.|||..|....| .....::..:.:|:..
Mouse   235 IDFSLYNANVNLFCIIRLLAEFPATGGLLTSWQFYSVKLLRYVSYYDYFIASCEVIFCIFLFVFI 299

  Fly   394 AQTLAVKLWYEPHLLKSVWNKLDLFIFMVNVLVVVLVVLRES----LVASMMKKVEGASKMEFID 454
            .|.|.....::....:||||.|::.:.::..|.|........    |:..::|..:     .:.|
Mouse   300 IQELRKVNEFKSAYFRSVWNWLEMLLLLLCFLAVSFYAYCNMQSFLLLGQLLKNTD-----SYPD 359

  Fly   455 FRRPSRMHQLTTITIGFLICITTLRLW-RVLQFASVFKLFTRTLYLAWSAVASTAIAIVIFLIGF 518
            |...:..|    |....:|.||....| ::.:|.|    |..|:    |.::||....:..::||
Mouse   360 FYFLAYWH----IYYNNVIAITIFFAWIKIFKFIS----FNETM----SQLSSTLSRCMKDIVGF 412

  Fly   519 CFAVVTINGNYS--------------SNFNKLVKSMVMCMCYSFGFSAQVKPSELFHGGKW-LGI 568
            ......|...|:              |.|...:.:....:...|.|:.       .....| ||.
Mouse   413 AIMFFIIFSAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAG-------IQQANWILGP 470

  Fly   569 LCYGVLAFVIIVLLINVFVSLINDYFTVAKTIRDSERENRITFFEFLVVEFSGVLGRFRKLPCWR 633
            :.:....|.:..:|:|:|:::|||.::..|.  |.....|..|          .||:..:..|:
Mouse   471 IYFITFIFFVFFVLLNMFLAIINDTYSEVKA--DYSIGRRPDF----------ELGKIIQKSCF- 522

  Fly   634 RNYVRNGRTVAENVSRKL----------DSMDRQRLMRRRLRQGRHHVSRPVSAEDALLEYKDRG 688
                        ||..||          ..|....|.:|..|.|  .....:...:.:..:|:|.
Mouse   523 ------------NVLEKLRLKKAQAKEEKKMQTTDLAQRARRDG--FDESEIQEAEQMKRWKERL 573

  Fly   689 DKMVNVHYILNIQLTLIRMFLFDEYVEWPQEQQKQ 723
            :|.   :|...||         |:|....|::.::
Mouse   574 EKK---YYSTEIQ---------DDYQPVTQQEFRE 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brv3	NP_001284831.1	PKD_channel	170..595	CDD:285288	110/481 (23%)
Pkd2l2	XP_017173433.1	PKD_channel	78..499	CDD:369653	110/483 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3599
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810