Protein Alignment brv3 and Pkd2l2

DIOPT Version :9

• Sequence 1: NP_001284831.1
• Gene: brv3 / 31246
• FlyBaseID: FBgn0040333
• Length: 750
• Species: Drosophila melanogaster
• Sequence 2: NP_001099626.1
• Gene: Pkd2l2 / 291683
• RGDID: 1310272
• Length: 621
• Species: Rattus norvegicus
• Alignment Length: 688
• Identity: 152/688 - (22%)
• Similarity: 266/688 - (38%)
• Gaps: 179/688 - (26%)

  Fly   110 TSRY-RNYKLNDQYKMIAHDLFIYGPYFLCLMCLVLVTRDQTLYHNTRIITDLFM---YNHTDYT 170
            ||:: .:|:...:......:|.:|..:.:.|..|...|.:..:|:..::::.||:   ....:.:
  Rat    12 TSKHDLHYRREAEVNTTLEELLLYFIFLINLCILTFGTVNPHMYYLNKVMSSLFVDTSLPDDERS 76

  Fly   171 GLQEVYFLNQLFDFIESTLVLA------FNSNSTESGSPGWAHAEQSVLLGVMRLRQLRVSNPQV 229
            ..:.:..:.:.:.|:|..||..      :.:...:|.........:::||||.|:|||||.|...
  Rat    77 SFRSIRSITEFWKFMEGPLVEGLYWDSWYGNTQLDSVKNSSLIYYENILLGVPRVRQLRVRNSTC 141

  Fly   230 GLGP---PKFSDTYY--------MPDWQLPYRKLHYSDKYWR-----IYEPWIPIKMGFEFLDAL 278
            .:.|   ...||.|.        ..|:.|.:      |..||     ...||
  Rat   142 QVYPAFQSLASDCYNKYTAENEDFSDFGLKH------DPEWRHSAPSSTAPW------------- 187

  Fly   279 LMNFDHVGSLNSYPELAGYVSLLARSAANSMKVIDYLSENHWLTLNTSAVFIDFTLYNVDVNLFS 343
                 |.|.:..|.: .||:..|::|.:.:...:..|.:|:|:...|.||||||:|||.:||||.
  Rat   188 -----HWGFVGVYRD-GGYMVTLSKSKSETKAKLADLRQNNWIGRGTRAVFIDFSLYNANVNLFC 246

  Fly   344 ICTLRVEKTPFGGIVPDVQVDSAKLLENVDQMPYTGLLA-----LLIYVLVFIQFAQTLAVKLWY 403
            |..|..|....|||:...|..|.||:..|..  |...:|     ..|::||||  .|.|.....:
  Rat   247 IIRLLAEFPATGGILTSWQFYSVKLIRYVSY--YDHFIASCEIIFCIFLLVFI--TQELRKLNEF 307

  Fly   404 EPHLLKSVWNKLDLFIFMVNVLVVVLVVLRES-----------LVASMMKKVEGASKMEFIDFRR 457
            :....:||||.::|       |::||..|..|           |:..:::..|     .:.||..
  Rat   308 KSAYFRSVWNWIEL-------LLLVLCFLAVSFYAYCNVQCFLLLGQLLRSTE-----SYPDFYF 360

  Fly   458 PSRMHQLTTITIGFLICITTLRLW-RVLQFASVFKLFTRTLYLAWSAVAST---------AIAIV 512
            .:..|    |....:|.||....| ::.:|.|    |..|:    |.::||         ..||:
  Rat   361 LAYWH----IYYNNIIAITIFFAWIKIFKFIS----FNETM----SQLSSTLSRCMKDIVGFAIM 413

  Fly   513 IFLIGFCFAVVT--INGNYSSNFNKLVKSM---VMCMCYSFGFSAQVKPSELFHGGKW-LGILCY 571
            .|:|.|.:|.:.  :.|:...:|:....|:   ...:...|.|:.       .....| ||.:.:
  Rat   414 FFIIFFAYAQLAFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAG-------IQQANWILGPIYF 471

  Fly   572 GVLAFVIIVLLINVFVSLINDYFTVAKTIRDSERENRITFFEFLVVEFSGVLGRFRKLPCWRRNY 636
            ....|.:..:|:|:|:::|||.::..|.  |.....|..|          .||...|..|:
  Rat   472 ITFIFFVFFVLLNMFLAIINDTYSEVKA--DYSIGRRPDF----------ELGSIIKKSCF---- 520

  Fly   637 VRNGRTVAENVSRKLDSMDRQRLMRRRLRQGRHHVSRPVSAEDALLEYKDRG------------- 688
                     |:..||           |||:.:::..:.:.....|.:.:..|
  Rat   521 ---------NILEKL-----------RLRKAQNNEDKKMKTSVDLAQARKEGFDESEIQEARQMK 565

  Fly   689 ---DKMVNVHYILNIQLTLIRMFLFDEYVEWPQEQQKQ 723
               :::...:|...||         |:|....|::.::
  Rat   566 RWKERLEKKYYSTEIQ---------DDYQPVTQQEFRE 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brv3	NP_001284831.1	PKD_channel	170..595	CDD:285288	119/478 (25%)
Pkd2l2	NP_001099626.1	PKD_channel	76..497	CDD:285288	119/480 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3599
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810