Protein Alignment brv3 and Pkd1l3

DIOPT Version :9

• Sequence 1: NP_001284831.1
• Gene: brv3 / 31246
• FlyBaseID: FBgn0040333
• Length: 750
• Species: Drosophila melanogaster
• Sequence 2: XP_017168310.1
• Gene: Pkd1l3 / 244646
• MGIID: 2664670
• Length: 2206
• Species: Mus musculus
• Alignment Length: 599
• Identity: 134/599 - (22%)
• Similarity: 241/599 - (40%)
• Gaps: 109/599 - (18%)

  Fly    42 LVSIVIVLIFQFLIGDPIKFVILSI--------------DR--------ALWPPRIYIPPRCDKD 84
            ::|:::.::....|..|||.:.|::              |:        |||       .:|...
Mouse  1596 VISMMLSVLQDIFISQPIKVIFLTLLFSLMANHMPWLNKDKEQHARRIVALW-------AKCPWS 1653

  Fly    85 EMDEKEERRDFLKQRLINKRANLMLTSRYRNYKLNDQYKMIAHDLFIYGPYFLCLMCLVLVTRDQ 149
            ....:::.........:|   ||...:| :.:|  .|...:.....:...:...||..|...:|.
Mouse  1654 APGLRDKNNPIYTAPAMN---NLAKPTR-KAWK--KQLSKLTGGTLVQILFLTLLMTTVYSAKDS 1712

  Fly   150 TLYHNTRIITDLFMYNHTDYTGLQEVYFLNQLFDFIESTLVLAFNSNSTESGSPGWAHAEQSVLL 214
            :.:...|.|...|.:..::...:::.|      .:...||:     .:......|:.....|.||
Mouse  1713 SRFFLHRAIWKRFSHRFSEIKTVEDFY------PWANGTLL-----PNLYGDYRGFITDGNSFLL 1766

  Fly   215 GVMRLRQLRVSNPQVGLG--------PPKFSD--TYYMPDWQLPYRKLHYSDKYWRIYEPWIPIK 269
            |.:.:||.|:.|.....|        ||:..:  ..|...|..|...:...|..|
Mouse  1767 GNVLIRQTRIPNDIFFPGSLHKQMKSPPQHQEDRENYGAGWVPPDTNITKVDSIW---------- 1821

  Fly   270 MGFEFLDALLMNFDHVGSLNSYP---ELA-----GYVSLLARSAANSMKVIDYLSENHWLTLNTS 326
                       ::.:..||..||   |||     |||..|.|:.:.:.:|:.:|.:..||...|.
Mouse  1822 -----------HYQNQESLGGYPIQGELATYSGGGYVVRLGRNHSAATRVLQHLEQRRWLDHCTK 1875

  Fly   327 AVFIDFTLYNVDVNLFSICTLRVEKTPFGGIVPDVQVDSAKLLEN--------VDQMPYTGLLAL 383
            |:|::||::|.:|||....||.:|.:..|..:..:|:||...|::        |.|:.|    .|
Mouse  1876 ALFVEFTVFNANVNLLCAVTLILESSGVGTFLTSLQLDSLTSLQSSERGFAWIVSQVVY----YL 1936

  Fly   384 LIYVLVFIQFAQTLAVKLWYEPHLLKSVWNKLDLFIFMVNVLVVVLVVLRESLVASMMKKVEGAS 448
            |:....|||..:....:|.:    .....|.||..|.:::..::.|.:...||:...|::.. ..
Mouse  1937 LVCYYAFIQGCRLKRQRLAF----FTRKRNLLDTSIVLISFSILGLSMQSLSLLHKKMQQYH-CD 1996

  Fly   449 KMEFIDFRRPSRMHQLTTITIGFLICITTLRLWRVLQFASVFKLFTRTLYLAWSAVASTAIAIVI 513
            :..||.|....|::...|...|||:...|:|:|.:|:..:..::..:||..||..|....:.||:
Mouse  1997 RDRFISFYEALRVNSAVTHLRGFLLLFATVRVWDLLRHHAQLQVINKTLSKAWDEVLGFILIIVV 2061

  Fly   514 FLIGFCFAVVTINGNYSSNFNKLVKSMVMCMCYSFGFSAQVKPSELFHGGKWLGILCYGVLAFVI 578
            .|..:......:.|...|::....:|:|..:....|.|   |..|:......||.|.  ||:.:|
Mouse  2062 LLSSYAMTFNLLFGWSISDYQSFFRSIVTVVGLLMGTS---KHKEVIALYPILGSLL--VLSSII 2121

  Fly   579 I--VLLINVFVSLI 590
            :  :::||:|||.|
Mouse  2122 LMGLVIINLFVSAI 2135

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brv3	NP_001284831.1	PKD_channel	170..595	CDD:285288	110/449 (24%)
Pkd1l3	XP_017168310.1	CLECT	37..142	CDD:153057
		Atrophin-1	<137..>472	CDD:367360
		Herpes_BLLF1	<325..652	CDD:282904
		GPS	1041..1079	CDD:366827
		PLAT_polycystin	1151..1269	CDD:238850
		PKD_channel	1729..2139	CDD:369653	110/453 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3599
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10877
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910